Recombinant Murine MDC (CCL22) 0 ComentariosSubmit a Review Detalles del Producto Nùmero de Catalogo 250-23 Descripcion MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells, and exerts HIV-suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity, but retains HIV-suppressive activity. Recombinant Murine MDC is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. Source: E.coli Synonyms: Macrophage-Derived Chemokine, CCL22, STCP-1, ABCD-1 AA Sequence: GPYGANVEDS ICCQDYIRHP LPSRLVKEFF WTSKSCRKPG VVLITVKNRD ICADPRQVWV KKLLHKLS Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract murine BW5147.3 cells using a concentration range of 1-30 ng/ml. Calculated Molecular Weight: 7.8 kDa Accession Number: O88430 Gene ID: 20299 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Mouse References PubMed SDS Búsqueda del CoA Product Line Country Of Origin: USA Not for human use. Research Interest AIDS/HIV Chemotaxis Immune System Wound Healing product.subtitle.recentcitations Primer autor Lee, K M Titulo CCL17 in Inflammation and Pain. Citar Journal of immunology (Baltimore, Md. : 1950); 205(1) pg213-222 PudMed id 32461237 Primer autor Sakai, R Titulo Tocilizumab monotherapy uncovered the role of the CCL22/17-CCR4+ Treg axis during remission of crescentic glomerulonephritis. Citar Clinical & translational immunology; 9(11) pge1203 PudMed id 33163184 Primer autor Yagawa, Y Titulo Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy. Citar Scientific Reports; 7(1) pg15996 PudMed id 29167448
