MIP-1γ is a CC chemokine found in murine blood and a wide variety of murine tissues, with no known human homolog. MIP-1γ signals through the CCR1 receptor. MIP-1γ chemoattracts neutrophils, and also inhibits colony formation of bone marrow myeloid immature progenitors. MIP-1γ contains six cysteines, including the four highly conserved cysteine residues present in CC chemokines. Recombinant Murine MIP-1γ is an 11.6 kDa protein containing 101 amino acid residues.
Macrophage Inflammatory Protein-1γ, CCL9/10, MRP2, CCF18
QITHATETKE VQSSLKAQQG LEIEMFHMGF QDSSDCCLSY NSRIQCSRFI GYFPTSGGCT RPGIIFISKR GFQVCANPSD RRVQRCIERL EQNSQPRTYK Q
≥ 98% by SDS-PAGE gel and HPLC analyses.
Determined by its ability to chemoattract human neutrophils using a concentration range of 0.1-10.0 ng/ml.
Calculated Molecular Weight:
Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)
Not for human use.