Recombinant Murine MIP-3β (CCL19) 1 ReviewsSubmit a Review Product Details Catalogue Number: 250-27B Description: MIP-3β is a CC chemokine, expressed in the thymus, lymph nodes, and in activated bone marrow stromal cells that signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes, and myeloid progenitor cells. Human MIP-3β is active on murine cells. Recombinant Murine MIP-3β is a 9.2 kDa protein containing 83 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. Source: E.coli Synonyms: Macrophage Inflammatory Protein-3β, CCL19, ELC, Exodus-3, SCYA19 AA Sequence: GANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRGYQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract activated human T cells expressing the CCR7 receptor. The ED50 for this effect is 30-90 ng/ml. Calculated Molecular Weight: 9.2 kDa Accession Number: O70460 Gene ID: 24047 crossreactivity: Human, Human + Mouse, Monkey, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Wound Healing product.subtitle.recentcitations First Author Reijmers, R M Title Disruption of heparan sulfate proteoglycan conformation perturbs B-cell maturation and APRIL-mediated plasma cell survival. Citation Blood; 117(23) pg6162-71 PubMed Id 21471524 First Author López-Cotarelo, P Title A novel MEK-ERK-AMPK signaling axis controls chemokine receptor CCR7-dependent survival in human mature dendritic cells. Citation The Journal of Biological Chemistry; 290(2) pg827-40 PubMed Id 25425646 First Author Pabbisetty, S K Title Peripheral tolerance can be modified by altering KLF2-regulated Treg migration. Citation Proceedings of the National Academy of Sciences of the United States of America; 113(32) pgE4662-70 PubMed Id 27462110 product.subtitle.productreviews Existing reviews migration assays works well for dendritic cells in migration assays! From: Caitlin | Date: 13/07/2020 × migration assays works well for dendritic cells in migration assays! From: Caitlin | Date: 13/07/2020 Close
