Recombinant Rat EGF 0 ReviewsSubmit a Review Product Details Catalogue Number: 400-25 Description: EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor). Recombinant Rat EGF is a 6.2 kDa globular protein containing 54 amino acid residues, including 3 intramolecular disulfide bonds. Source: E.coli Synonyms: Epidermal Growth Factor, Urogastrone, URG AA Sequence: MNSNTGCPPS YDGYCLNGGV CMYVESVDRY VCNCVIGYIG ERCQHRDLRW WKLR Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 was determined by a cell proliferation assay using BALB/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. Calculated Molecular Weight: 6.2 kDa Accession Number: P07522 Gene ID: 25313 crossreactivity: Human, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Organoids Angiogenesis/Cardiovascular Cancer Cell Culture Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing Diabetes/Weight Regulation product.subtitle.recentcitations First Author Silvestroff, L Title Neural and oligodendrocyte progenitor cells: transferrin effects on cell proliferation. Citation ASN Neuro; 5(1) pge00107 PubMed Id 23368675 First Author Li, J Title Autophagy-dependent generation of Axin2+ cancer stem-like cells promotes hepatocarcinogenesis in liver cirrhosis. Citation Oncogene; 36(48) pg6725-6737 PubMed Id 28783177 First Author Rangel, E B Title Kidney-derived c-kit Citation Scientific Reports; 8(1) pg14723 PubMed Id 30283057
