Growth Factors & Cytokines

Recombinant Rat EGF

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Product Details

Catalogue Number: 400-25
Description:

EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor). Recombinant Rat EGF is a 6.2 kDa globular protein containing 54 amino acid residues, including 3 intramolecular disulfide bonds.

Source: E.coli

Synonyms: Epidermal Growth Factor, Urogastrone, URG

AA Sequence: MNSNTGCPPS YDGYCLNGGV CMYVESVDRY VCNCVIGYIG ERCQHRDLRW WKLR

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: The ED50 was determined by a cell proliferation assay using BALB/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.

Calculated Molecular Weight: 6.2 kDa

Accession Number: P07522

Gene ID: 25313

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

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