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Growth Factors & Cytokines

Recombinant Rat FGF-10

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Detalles del Producto

Nùmero de Catalogo 400-42
Descripcion
Recombinant Rat FGF-10

FGF‐10 is a heparin‐binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF‐10 is most related to KGF/FGF‐7, and is expressed during the development and, preferentially, in adult lungs. It signals through FGFR 2b. Recombinant Rat FGF‐10 is a 20.2 kDa protein consisting of 180 amino acid residues.

Source: E.coli

Synonyms: Fibroblast Growth Factor‐10, FGFA, Keratinocyte Growth Factor‐2

AA Sequence: MQALGQDMVS PEATNSSSSS SSSSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR GQKTRRKNTS AHFLPMVVHS

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Assay #1: Determined by dose-dependent ability to reduce tetrazolium salt, WST-8, by dehydrogenase activities of BaF3 cells expressing FGF receptors using Cell Counting Kit-8 (CCK-8).

Assay #2: Determined by a cell proliferation assay using 4MBr-5 cells. The expected ED50 for this effect is 1-5 ng/ml.

Calculated Molecular Weight: 20.2 kDa

Accession Number: P70492

Gene ID: 25443

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

Country Of Origin: USA

Not for human use.

Research Interest