Recombinant Rat SDF-1α (CXCL12) 0 ReviewsSubmit a Review Product Details Catalogue Number: 400-32A Description: SDF-1α and β are stromal-derived, CXC chemokines that signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV-suppressive activity in cells expressing the CXCR4 receptor. Human and murine SDF-1 proteins act across species. SDF-1α and β contain the four highly conserved cysteine residues present in CXC chemokines. The mature SDF-1α protein is the result of alternative splicing of the SDF-1 gene and contains 68 amino acid residues. Recombinant Rat SDF-1α is a 7.9 kDa protein containing 68 amino acid residues. Source: E.coli AA Sequence: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNK Synonyms: Stromal-Cell Derived Factor-1, CXCL12, PBSF Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 50.0-100.0 ng/ml. Calculated Molecular Weight: 7.9 kDa Accession Number: Q9QZD1 Gene ID: 24772 crossreactivity: Human, Human + Rat, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest AIDS/HIV Chemotaxis Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing product.subtitle.recentcitations First Author Yang, J Title CXCR4 receptor overexpression in mesenchymal stem cells facilitates treatment of acute lung injury in rats. Citation The Journal of Biological Chemistry; 290(4) pg1994-2006 PubMed Id 25492872 First Author Chen, D Title Crosstalk between SDF-1/CXCR4 and SDF-1/CXCR7 in cardiac stem cell migration. Citation Scientific Reports; 5 pg16813 PubMed Id 26578388 First Author Renko, O Title SDF1 gradient associates with the distribution of c-Kit+ cardiac cells in the heart. Citation Scientific Reports; 8(1) pg1160 PubMed Id 29348441