SAG Product Details Catalogue Number: 9128694 Description: SAG is a cell-permeable agonist for smoothened, a key part of the hedgehog signaling pathway. It directly activates smoothened and can prevent cyclopamine inhibition. SAG can be used to enhance the neuronal differentiation of human induced pluripotent stem cells and aid in the survival and proliferation of neuronal precursors. It is reported to prevent drug induced brain injury and stimulate normal cerebellum after injection in mice with an induced Down’s syndrome-like condition. Synonyms: AC1NR49D, CHEMBL1221983 Application: Formulation: Crystalline solid Chemical Name: 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide Molecular Formula: C28H28ClN3OS Molecular Weight: 490.1 CAS Number: 912545-86-9 Purity: ≥98% Note: Product supplied by Biogems Country Of Origin: USA Not for human use. CoA Search Product Line Research Interest Stem Cells & Differentiation
