Anticorps Monoclonaux


Anti-Mouse/Rat TNF-alpha SAFIRE Purified (Clone#: TN3-19)

Product Details

Catalogue Number: 84412-25
The TN3-19 monoclonal antibody reacts with mouse and rat tumor-necrosis (TNF) alpha proteins. It is not cross-reactive with mouse TNF-Beta or human TNF. TNF-Alpha is a pleiotropic pro-inflammatory cytokine secreted by various cells, including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands, and signals through two receptors, TNFR1 and TNFR2. TNF-α is cytotoxic to a wide variety of tumor cells, and is an essential factor in mediating the immune response against bacterial infections. TNF-α also plays a role in the induction of septic shock, autoimmune diseases, rheumatoid arthritis, inflammation, and diabetes. The TN3-19 antibody is reported to be a neutralizing antibody.

Source: Isotype: Armenian Hamster IgG; Clone#: TN3-19


Product supplied by Biogems

SAFIRE (Sodium Azide Free Immensely Reduced Endotoxin) products are BioGems’ line of functional antibodies that can be used for activation, blocking, and neutralization studies. They are manufactured carrier and sodium azide free, with immensely reduced endotoxin levels of 0.01 EU/ug or lower for in vivo and in vitro applications.

Country Of Origin: USA

Not for human use.

Research Interest