Anti-Human TIM3 SAFIRE Purified (Clone#: F38-2E2) Détails du Produit Catalog Number: 78211-25 Description: The F38-2E2 monoclonal antibody specifically reacts with human T cell immunoglobulin and mucin domain containing protein (TIM3), a transmembrane molecule found on monocytes, macrophages, dendritic cells, and activated T cell types such as Treg, Th1, and Th17. TIM3 can exist in soluble and membrane bound forms and the relevant ligand for the protein is Galectin-9. It plays a role in the creation of immunological tolerances, the secretion of Th1 and Th17 related cytokines, and HIV infection. Source: Isotype: Mouse IgG1, kappa; Clone#: F38-2E2 Note: Product supplied by BiogemsSAFIRE (Sodium Azide Free Immensely Reduced Endotoxin) products are BioGems’ line of functional antibodies that can be used for activation, blocking, and neutralization studies. They are manufactured carrier and sodium azide free, with immensely reduced endotoxin levels of 0.01 EU/ug or lower for in vivo and in vitro applications. Cross Reactivity: Human Research Interest Immune System Product Line Country Of Origin: USA Not for human use.