EX 527 Product Details Catalogue Number: 4989833 Description: EX 527 is a selective inhibitor of NAD-dependent deacetylase sirtuin-1 (SIRT1) to the exclusion of histone deacetylases (HDACs) and other sirtuins. It is reported that inhibiting SIRT1 is associated with increasing insulin sensitivity and effecting other metabolic regulatory functions. EX 527 was used to determine that the inactivation of SirT1 stimulates tumor cell proliferation. Synonyms: 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide, Selisistat, EX527, SIRT1 Inhibitor III Application: Formulation: Crystalline solid Chemical Name: 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide Molecular Formula: C13H13ClN2O Molecular Weight: 248.7 CAS Number: 49843-98-3 Purity: ≥98% Note: Product supplied by Biogems Country Of Origin: USA Not for human use. CoA Search Product Line Research Interest Cancer
