GSK923295 Détails du Produit Catalog Number: 1083707 Description: GSK923295 is a potent and selective mitotic kinesin Centromere protein E (CENP-E) inhibitor, a protein that accumulates in the G2 phase of the cell cycle. It is proposed to be one of the motors responsible for mammalian chromosome movement and spindle elongation. GSK923295 induces mitotic arrest and chromosome alignment failure. It is reported to be a potent inhibitor of tumor cell growth, which is further enhanced when MEK/ERK signaling is also inhibited. Synonyms: GSK-923295 Application: Formulation: Crystalline solid Chemical Name: 3-chloro-N-[(2S)-1-[[2-(dimethylamino)acetyl]amino]-3-[4-[8-[(1S)-1hydroxyethyl]imidazo[1,2-a]pyridin-2-yl]phenyl]propan-2-yl]-4-propan-2-yloxybenzamide Molecular Formula: C32H38ClN5O4 Molecular Weight: 592.1 CAS Number: 1088965-37-0 Purity: ≥98% Note: Product supplied by Biogems Research Interest Cancer Product Line Country Of Origin: USA Not for human use.
