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Small Molecules

Biogems

GSK923295

Détails du Produit

Catalog Number: 1083707
Description:

GSK923295 is a potent and selective mitotic kinesin Centromere protein E (CENP-E) inhibitor, a protein that accumulates in the G2 phase of the cell cycle. It is proposed to be one of the motors responsible for mammalian chromosome movement and spindle elongation. GSK923295 induces mitotic arrest and chromosome alignment failure. It is reported to be a potent inhibitor of tumor cell growth, which is further enhanced when MEK/ERK signaling is also inhibited.

Synonyms: GSK-923295

Application:

Formulation:
Crystalline solid
Chemical Name:
3-chloro-N-[(2S)-1-[[2-(dimethylamino)acetyl]amino]-3-[4-[8-[(1S)-1hydroxyethyl]imidazo[1,2-a]pyridin-2-yl]phenyl]propan-2-yl]-4-propan-2-yloxybenzamide
Molecular Formula:

C32H38ClN5O4

Molecular Weight:
592.1
CAS Number:
1088965-37-0
Purity:
≥98%

Note:

Product supplied by Biogems

Research Interest

Country Of Origin: USA

Not for human use.