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Pre-Coated ELISA Kits

Biogems

Human IL-6 Pre-Coated ELISA Kit

Détails du Produit

Catalog Number: BGK05231
Description:

IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R α and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. The BioGems Human IL-6 Pre-Coated ELISA (Enzyme-Linked Immunosorbent Assay) kit is a solid phase immunoassay specially designed to measure human IL-6 with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for IL-6. It contains E.coli-expressed recombinant human IL-6. The detection antibody is a biotinylated goat polyclonal antibody specific for IL-6. The kit is analytically validated with ready to use reagents.

Sandwich ELISA:

Assay Type:
Solid Phase Sandwich ELISA: 96-Well Strip Plate
Sensitivity:
<0.3 pg/ml
Range:
4.69 pg/mL – 300 pg/mL
Specificity:
Natural and recombinant Human IL-6
Uniprot:
P05231
Interference:
No detectable cross-reactivity with other relevant proteins

Note:

Product supplied by Biogems

Country Of Origin: USA

Not for human use.