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Pre-Coated ELISA Kits

Biogems

Human Neuregulin Pre-Coated ELISA Kit

Détails du Produit

Catalog Number: BGK02297
Description:

Neuregulin/Heregulin is a family of structurally related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3 and NRG4). To date, there are over 14 soluble and transmembrane proteins derived from the NRG1 gene. Proteolytic processing of the extracellular domain of the transmembrane NRG1 isoforms releases soluble growth factors. HRG1-β1 contains an Ig domain and an EGF-like domain; the latter is necessary for direct binding to receptor tyrosine kinases erb3 and erb4. This binding induces erb3 and erb4 heterodimerization with erb2, stimulating intrinsic kinase activity that leads to tyrosine phosphorylation. The BioGems Human Neuregulin Pre-Coated ELISA (Enzyme-Linked Immunosorbent Assay) kit is a solid phase immunoassay specially designed to measure Neuregulin with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for Neuregulin. It contains E.coli-expressed recombinant Neuregulin. The detection antibody is a biotinylated goat polyclonal antibody specific for Neuregulin. The kit is analytically validated with ready to use reagents.

Sandwich ELISA:

Assay Type:
Solid Phase Sandwich ELISA: 96-Well Strip Plate
Sensitivity:
<10 pg/ml 
Range:
  62.5pg/ml-4000pg/ml
Specificity:
Natural and recombinant Human Neuregulin
Uniprot:
 Q02297
Interference:
No detectable cross-reactivity with other relevant proteins

Note:

Product supplied by Biogems

Country Of Origin: USA

Not for human use.