LY2157299 Product Details Catalogue Number: 7007224 Description: LY2157299 is a potent inhibitor of Transforming Growth factor-Beta Receptor I (TGF-BetaR). TGF-Beta1 is involved in the control of cell growth, proliferation, differentiation, and apoptosis. LY2157299 is reported to disrupt Smad-2 phosphorylation in Human Umbilical Vein Endothelial Cells (HUVEC) and inhibit the growth and migration of tumor cells. Synonyms: LY 2157299, LY-2157299, Galunisertib Application: Formulation: Crystalline solid Chemical Name: 4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide Molecular Formula: C22H19N5O Molecular Weight: 369.4 CAS Number: 700874-72-2 Purity: ≥98% Note: Product supplied by Biogems Country Of Origin: USA Not for human use. CoA Search Product Line Research Interest Cancer
