Rat IL-1α Pre-Coated ELISA Kit Détails du Produit Catalog Number: BGK16598 Description: IL-1a is a non-secreted, proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes, and other epithelial cells. Both IL-1a and IL-1b bind to the same receptor and have similar, if not identical, biological properties. These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity, and the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1b is a secreted cytokine, IL-1a is predominantly a cell-associated cytokine. The BioGems Rat IL-1α Pre-Coated ELISA (Enzyme-Linked Immunosorbent Assay) kit is a solid phase immunoassay specially designed to measure IL-1α with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for IL-1alpha. It contains E.coli-expressed recombinant IL-1alpha. The detection antibody is a biotinylated goat polyclonal antibody specific for IL-1α. The kit is analytically validated with ready to use reagents. Sandwich ELISA: Assay Type: Solid Phase Sandwich ELISA: 96-Well Strip Plate Sensitivity: <0.5pg/ml Range: 4.69pg/ml-300pg/ml Specificity: Natural and recombinant Rat IL-1a Uniprot: P16598 Interference: No detectable cross-reactivity with other relevant proteins Note: Product supplied by Biogems Product Line Country Of Origin: USA Not for human use.