Recombinant Human Chemerin 0 ReviewsSubmit a Review Product Details Catalogue Number: 300-66 Description: Chemerin is a secreted chemoattractant protein that can signal through the chemokine-like receptor-1 (CMKLR1). It is expressed in various tissues, including white adipose tissue, and circulates in blood as an inactive 143 amino acid precursor protein. Biologically active Chemerin is generated by proteolytic removal of C-terminal residues by several circulating proteases. Chemerin acts as a chemoattractant for cells expressing the CMKLR1 receptor, which includes certain dendritic cells, macrophages, and adipocytes. Recombinant Human Chemerin is a 15.6 kDa protein consisting of 135 amino acid residues. Source: E.coli Synonyms: Tazarotene-induced gene 2 (TIG2), RARRES2 AA Sequence: ELTEAQRRGL QVALEEFHKH PPVQWAFQET SVESAVDTPF PAGIFVRLEF KLQQTSCRKR DWKKPECKVR PNGRKRKCLA CIKLGSEDKV LGRLVHCPIE TQVLREAEEH QETQCLRVQR AGEDPHSFYF PGQFA Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human immature dendritic cells using a concentration range of 1.0-100.0 ng/ml. Calculated Molecular Weight: 15.6 kDa Accession Number: Q99969 Gene ID: 5919 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Mouse, Zebra Fish References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Diabetes/Weight Regulation Immune System Lipid Metabolism product.subtitle.recentcitations First Author Lahvic, J L Title Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132. Citation Proceedings of the National Academy of Sciences of the United States of America; 115(37) pg9252-9257 PubMed Id 30139917
