Facteurs de Croissance et Cytokines

Recombinant Human FGF-17

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Product Details

Catalogue Number: 100-27
Description:

FGF-17 is a heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-17 signals through FGFR 1c, 2c, 3c, and 4. FGF-17 promotes the induction and patterning of brain development during embryogenesis. Recombinant Human FGF-17 is a 22.7 kDa protein consisting of 195 amino acid residues.

Source: E.coli

Synonyms: Fibroblast Growth Factor-17, FGFH

AA Sequence: MTQGENHPSP NFNQYVRDQG AMTDQLSRRQ IREYQLYSRT SGKHVQVTGR RISATAEDGN KFAKLIVETD TFGSRVRIKG AESEKYICMN KRGKLIGKPS GKSKDCVFTE IVLENNYTAF QNARHEGWFM AFTRQGRPRQ ASRSRQNQRE AHFIKRLYQG QLPFPNHAEK QKQFEFVGSA PTRRTKRTRR PQPLT

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg.

Calculated Molecular Weight: 22.7 kDa

Accession Number: O60258

Gene ID: 8822

Note:

250μg is the largest vial size for this product.
Larger sizes supplied as multiple 250μg vials.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Zhang, X
Title
Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family.
Citation
The Journal of Biological Chemistry; 281(23) pg15694-700
PubMed Id
First Author
Savchenko, E
Title
FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes.
Citation
Scientific Reports; 9(1) pg9610
PubMed Id
First Author
Cinque, L
Title
MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B.
Citation
The EMBO Journal; pge105696
PubMed Id