Recombinant Human FGF-20 0 ReviewsSubmit a Review Product Details Catalogue Number: 100-41 Description: FGF-20 is a secreted, heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-20 signals through FGFR 2c and 3c, and is expressed during limb and brain development. Recombinant Human FGF-20 is a 23.2 kDa protein containing 209 amino acid residues. Source: E.coli Synonyms: Fibroblast Growth Factor-20, FGFK AA Sequence: PLAEVGGFLG GLEGLGQQVG SHFLLPPAGE RPPLLGERRS AAERSARGGP GAAQLAHLHG ILRRRQLYCR TGFHLQILPD GSVQGTRQDH SLFGILEFIS VAVGLVSIRG VDSGLYLGMN DKGELYGSEK LTSECIFREQ FEENWYNTYS SNIYKHGDTG RRYFVALNKD GTPRDGARSK RHQKFTHFLP RPVDPERVPE LYKDLLMYT Purity: ≥ 90% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 5 ng/ml in the presence of 1µg/ml heparin, corresponding to a specific activity of ≥ 2 x 105 units/mg. Calculated Molecular Weight: 23.2 kDa Accession Number: Q9NP95 Gene ID: 26281 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Note: 1mg will be provided as 2x500μg. crossreactivity: Human, Monkey, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Bone, Skeletal, Cartilage Cancer FGF Superfamily Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing product.subtitle.recentcitations First Author Savchenko, E Title FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes. Citation Scientific Reports; 9(1) pg9610 PubMed Id 31270389 First Author Westphal, S Title Fibroblast growth factor 8b induces uncoupling protein 1 expression in epididymal white preadipocytes. Citation Scientific Reports; 9(1) pg8470 PubMed Id 31186471 First Author Xiao, Z Title A computationally identified compound antagonizes excess FGF-23 signaling in renal tubules and a mouse model of hypophosphatemia. Citation Science Signaling; 9(455) pgra113 PubMed Id 27879395
