Recombinant Human Galectin-1 1 ReviewsSubmit a Review Product Details Catalogue Number: 450-39 Description: Lectins, of either plant or animal origin, are carbohydrate-binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T cells and T leukemia cell lines, and inhibits the protein phosphatase activity of CD45. Recombinant Human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues. Source: E.coli Synonyms: Galactose-specific lectin-1, Beta-galactoside-binding lectin L-14-I, Galaptin, 14 kDa lectin, S-LAC lectin-1 AA Sequence: ACGLVASNLN LKPGECLRVR GEVAPDAKSF VLNLGKDSNN LCLHFNPRFN AHGDANTIVC NSKDGGAWGT EQREAVFPFQ PGSVAEVCIT FDQANLTVKL PDGYEFKFPN RLNLEAINYM AADGDFKIKC VAFD Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 µg/ml with a peak response obtained at 250 µg/ml. Calculated Molecular Weight: 14.5 kDa Accession Number: P09382 Gene ID: 3956 crossreactivity: Human, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Apoptosis Cancer Immune System Neurobiology Stem Cells & Differentiation product.subtitle.recentcitations First Author Freitag, N Title Interfering with Gal-1-mediated angiogenesis contributes to the pathogenesis of preeclampsia. Citation Proceedings of the National Academy of Sciences of the United States of America; 110(28) pg11451-6 PubMed Id 23798433 First Author Carlos, C P Title Pharmacological treatment with galectin-1 protects against renal ischaemia-reperfusion injury. Citation Scientific Reports; 8(1) pg9568 PubMed Id 29934646 First Author Sweeney, J G Title Loss of GCNT2/I-branched glycans enhances melanoma growth and survival. Citation Nature Communications; 9(1) pg3368 PubMed Id 30135430 product.subtitle.productreviews Existing reviews good ELISA results Used for ELISA binding assay, got good results. Did not do any assays for function. From: Lucia | Date: 03/08/2021 × good ELISA results Used for ELISA binding assay, got good results. Did not do any assays for function. From: Lucia | Date: 03/08/2021 Close
