Recombinant Human HCC-1 (CCL14) (72 a.a.) 0 ReviewsSubmit a Review Product Details Catalogue Number: 300-38 Description: HCC-1 is a CC chemokine that signals through the CCR1 receptor and chemoattracts blood monocytes. It is secreted by various tissues, including skeletal muscle, heart, spleen, liver and bone marrow. Mature HCC-1 is found in four different forms, which are distinguished by differential N-terminal trucation and contain 74, 72, 71, or 66 amino acid residues. Recombinant Human HCC-1 is an 8.4 kDa protein consisting of 72 amino acids, including the four highly conserved residues present in CC chemokines. Source: E.coli Synonyms: Hemofiltrate CC Chemokine-1, CCL14, HCC-1/HCC-3, NCC-2 AA Sequence: TESSSRGPYH PSECCFTYTT YKIPRQRIMD YYETNSQCSK PGIVFITKRG HSVCTNPSDK WVQDYIKDMK EN Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration range of 5.0-20.0 ng/ml. Calculated Molecular Weight: 8.4 kDa Accession Number: Q16627 Gene ID: 6358 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Human, Mouse References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Bone, Skeletal, Cartilage Chemotaxis Immune System Wound Healing product.subtitle.recentcitations First Author Lee, A W Title A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins. Citation The Journal of Biological Chemistry; 294(29) pg11199-11212 PubMed Id 31167786 First Author Alenazi, Y Title Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets. Citation Scientific Reports; 8(1) pg6333 PubMed Id 29679010 First Author Buskermolen, J K Title Stimulation of oral fibroblast chemokine receptors identifies CCR3 and CCR4 as potential wound healing targets. Citation Journal of Cellular Physiology; 232(11) pg2996-3005 PubMed Id 28387445
