Facteurs de Croissance et Cytokines

Recombinant Human IFN-ω

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Product Details

Catalogue Number: 300-02J
Description:
Recombinant Human IFN-ω

IFN-ω is a type I interferon that can be induced by virus-infected leukocytes. Members of the type I interferon family, which includes IFN-α, IFN-β, and IFN-ω, signal through the IFNAR-1/IFNAR-2 receptor complex, and exert antiviral and antiproliferative activities.  IFN-ω exhibits about 75% sequence homology with IFN-α, and contains two conserved disulfide bonds that are necessary for full biological activity. Recombinant Human IFN-ω is a 19.9 kDa protein consisting of 172 amino acid residues.

Source: E.coli

Synonyms: IFN alpha II-1, IFNW1

AA Sequence: CDLPQNHGLL SRNTLVLLHQ MRRISPFLCL KDRRDFRFPQ EMVKGSQLQK AHVMSVLHEM LQQIFSLFHT ERSSAAWNMT LLDQLHTGLH QQLQHLETCL LQVVGEGESA GAISSPALTL RRYFQGIRVY LKEKKYSDCA WEVVRMEIMK SLFLSTNMQE RLRSKDRDLG SS

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: The ED50 was determined by a cytotoxicity assay using Human TF-1 cells is ≤ 0.01 ng/ml, corresponding to a specific activity of ≥ 1 x 108 units/mg.

Calculated Molecular Weight: 19.9 kDa

Accession Number: P05000

Gene ID: 3467

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Wang, J
Title
Alpha-Soluble NSF Attachment Protein Prevents the Cleavage of the SARS-CoV-2 Spike Protein by Functioning as an Interferon-Upregulated Furin Inhibitor.
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mBio; pge0244321
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First Author
Rodero, M P
Title
Detection of interferon alpha protein reveals differential levels and cellular sources in disease.
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The Journal of Experimental Medicine; 214(5) pg1547-1555
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Walter, J E
Title
Broad-spectrum antibodies against self-antigens and cytokines in RAG deficiency.
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The Journal of Clinical Investigation; 125(11) pg4135-48
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