Recombinant Human IL-16 (129 a.a.) 0 ReviewsSubmit a Review Product Details Catalogue Number: 200-16 Description: IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells, CD4+ monocytes, and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T cells. Human and murine IL-16 show significant cross-species reactivity. Recombinant Human IL-16 is a 13.3 kDa protein consisting of 129 amino acid residues. Source: E.coli Synonyms: LCF (Lymphocyte Chemoattractant Factor) AA Sequence: PDLNSSTDSA ASASAASDVS VESTAEATVC TVTLEKMSAG LGFSLEGGKG SLHGDKPLTI NRIFKGAASE QSETVQPGDE ILQLGGTAMQ GLTRFEAWNI IKALPDGPVT IVIRRKSLQS KETTAAGDS Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Not available. Calculated Molecular Weight: 13.3 kDa Accession Number: Q14005 Gene ID: 3603 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Human + Mouse, Mouse References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest AIDS/HIV Apoptosis Immune System Inflammation product.subtitle.recentcitations First Author Rothberg, J L Title Mtf2-PRC2 control of canonical Wnt signaling is required for definitive erythropoiesis. Citation Cell Discovery; 4 pg21 PubMed Id 29736258 First Author Ciraci, E Title Adult human circulating CD34â»Linâ»CD45â»CD133â» cells can differentiate into hematopoietic and endothelial cells. Citation Blood; 118(8) pg2105-15 PubMed Id 21715308 First Author Gilbert, L A Title DNA damage-mediated induction of a chemoresistant niche. Citation Cell; 143(3) pg355-66 PubMed Id 21029859