Recombinant Human IL-2

Détails du Produit

Catalog Number: 200-02

Description:

IL-2 is a powerful immunoregulatory lymphokine produced by T cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant Human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond.

Source: E.coli

Synonyms: Interleukin-2, T-cell growth factor (TCGF), Aldesleukin

AA Sequence: MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFAQSII STLT

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: The ED₅₀ as determined by the dose-dependent stimulation of murine CTLL-2 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.

Calculated Molecular Weight: 15.5 kDa

Accession Number: P60568

Gene ID: 3558

crossreactivity:

Bacteria, Chicken, Cow, Cow + Mouse, Dog, Human , Human + Hamster, Human + Mouse, Human + Virus, Monkey, Mouse, Rat

Research Interest

Stem Cells & Differentiation

Diabetes/Weight Regulation

Country Of Origin: USA

Not for human use.

First Author

Title

Citation

Pubmed

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Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression.

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1 Jul 2007

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Expansion of human T regulatory type 1 cells in the microenvironment of cyclooxygenase 2 overexpressing head and neck squamous cell carcinoma.

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Evaluation of ex vivo expanded human NK cells on antileukemia activity in SCID-beige mice.

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c-MAF-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont.

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FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells.

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Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry.

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Aggressive natural killer-cell leukemiaÂ mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target.

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HIV-1 targets L-selectin for adhesion and induces its shedding for viral release.

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The chimeric TAC receptor co-opts the T cell receptor yielding robust anti-tumor activity without toxicity.

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Myeloid apolipoprotein E controls dendritic cell antigen presentation and T cell activation.

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A conserved enhancer regulates Il9 expression in multiple lineages.

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iRGD synergizes with PD-1 knockout immunotherapy by enhancing lymphocyte infiltration in gastric cancer.

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Vaccination to prevent T cell subversion can protect against persistent hepacivirus infection.

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Synthetic TRuC receptors engaging the complete T cell receptor for potent anti-tumor response.

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Oncolytic adenovirus programmed by synthetic gene circuit for cancer immunotherapy.

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Sharma, G

Rapid selection and identification of functional CD8+ T cell epitopes from large peptide-coding libraries.

Nature Communications; 10(1) pg4553

7 Oct 2019

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Liu, J

Human placental trophoblast cells contribute to maternal-fetal tolerance through expressing IL-35 and mediating iTR35 conversion.

Nature Communications; 10(1) pg4601

10 Oct 2019

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Czystowska-Kuzmicz, M

Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma.

Nature Communications; 10(1) pg3000

5 Jul 2019

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Huntington, N D

CD45 links the B cell receptor with cell survival and is required for the persistence of germinal centers.

Nature Immunology; 7(2) pg190-8

0 Feb 2006

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Tada, T

MARCH8 inhibits HIV-1 infection by reducing virion incorporation of envelope glycoproteins.

Nature Medicine; 21(12) pg1502-7

0 Dec 2015

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Ahsan, M K

Loss of interleukin-2-dependency in HTLV-I-infected T cells on gene silencing of thioredoxin-binding protein-2.

Oncogene; 25(15) pg2181-91

6 Apr 2006

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Mandapathil, M

CD26 expression and adenosine deaminase activity in regulatory T cells (Treg) and CD4(+) T effector cells in patients with head and neck squamous cell carcinoma.

Oncoimmunology; 1(5) pg659-669

1 Aug 2012

22934258
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Munir, S

Characterization of T-cell responses against IÎºBÎ± in cancer patients.

Oncoimmunology; 1(8) pg1290-1296

1 Nov 2012

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Amarnath, S

Regulatory T cells and human myeloid dendritic cells promote tolerance via programmed death ligand-1.

PLoS Biology; 8(2) pge1000302

2 Feb 2010

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Tauzin, S

The naturally processed CD95L elicits a c-yes/calcium/PI3K-driven cell migration pathway.

PLoS Biology; 9(6) pge1001090

0 Jun 2011

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Bauler, T J

The FERM and PDZ domain-containing protein tyrosine phosphatases, PTPN4 and PTPN3, are both dispensable for T cell receptor signal transduction.

PLoS ONE; 3(12) pge4014

0 2008

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Brown, M E

Derivation of induced pluripotent stem cells from human peripheral blood T lymphocytes.

PLoS ONE; 5(6) pge11373

29 Jun 2010

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Campanella, G S

CXCL10 can inhibit endothelial cell proliferation independently of CXCR3.

PLoS ONE; 5(9) pge12700

13 Sep 2010

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Morteau, O

Renal transplant immunosuppression impairs natural killer cell function in vitro and in vivo.

PLoS ONE; 5(10) pge13294

12 Oct 2010

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Wu, X

Selective induction of DNA repair pathways in human B cells activated by CD4+ T cells.

PLoS ONE; 5(12) pge15549

16 Dec 2010

21179576
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Yamamoto, M

miR-155, a Modulator of FOXO3a Protein Expression, Is Underexpressed and Cannot Be Upregulated by Stimulation of HOZOT, a Line of Multifunctional Treg.

PLoS ONE; 6(2) pge16841

3 Feb 2011

21304824
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Eto, D

IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation.

PLoS ONE; 6(3) pge17739

14 Mar 2011

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Sengupta, S

Enhanced transduction and replication of RGD-fiber modified adenovirus in primary T cells.

PLoS ONE; 6(3) pge18091

28 Mar 2011

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Amarnath, S

Host-based Th2 cell therapy for prolongation of cardiac allograft viability.

PLoS ONE; 6(4) pge18885

29 Apr 2011

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Lu, J

Human ovarian tumor cells escape Î³Î´ T cell recognition partly by down regulating surface expression of MICA and limiting cell cycle related molecules.

PLoS ONE; 6(9) pge23348

0 2011

21935360
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Grangeiro de Carvalho, E

Plasmodium falciparum-infected erythrocytes and IL-12/IL-18 induce diverse transcriptomes in human NK cells: IFN-Î±/Î² pathway versus TREM signaling.

PLoS ONE; 6(9) pge24963

0 2011

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Gutierrez, A

Differentiation of chronic lymphocytic leukemia B cells into immunoglobulin secreting cells decreases LEF-1 expression.

PLoS ONE; 6(10) pge26056

0 2011

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Iguchi-Hashimoto, M

Overexpression of a minimal domain of calpastatin suppresses IL-6 production and Th17 development via reduced NF-ÎºB and increased STAT5 signals.

PLoS ONE; 6(10) pge27020

0 2011

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Sammicheli, S

IL-7 promotes CD95-induced apoptosis in B cells via the IFN-Î³/STAT1 pathway.

PLoS ONE; 6(12) pge28629

0 2011

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Chiang, C L

Day-4 myeloid dendritic cells pulsed with whole tumor lysate are highly immunogenic and elicit potent anti-tumor responses.

PLoS ONE; 6(12) pge28732

0 2011

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Common gamma chain cytokines promote rapid in vitro expansion of allo-specific human CD8+ suppressor T cells.

PLoS ONE; 6(12) pge28948

0 2011

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Nzounza, P

The scaffolding protein Dlg1 is a negative regulator of cell-free virus infectivity but not of cell-to-cell HIV-1 transmission in T cells.

PLoS ONE; 7(1) pge30130

0 2012

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Wang, C

Optimal population of FoxP3+ T cells in tumors requires an antigen priming-dependent trafficking receptor switch.

PLoS ONE; 7(1) pge30793

0 2012

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Tsuda, K

Calcineurin inhibitors suppress cytokine production from memory T cells and differentiation of naÃ¯ve T cells into cytokine-producing mature T cells.

PLoS ONE; 7(2) pge31465

0 2012

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Kunisawa, J

A pivotal role of vitamin B9 in the maintenance of regulatory T cells in vitro and in vivo.

PLoS ONE; 7(2) pge32094

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Munir, S

Natural CD4+ T-cell responses against indoleamine 2,3-dioxygenase.

PLoS ONE; 7(4) pge34568

0 2012

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Macrophages help NK cells to attack tumor cells by stimulatory NKG2D ligand but protect themselves from NK killing by inhibitory ligand Qa-1.

PLoS ONE; 7(5) pge36928

0 2012

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Guo, Z

DCs pulsed with novel HLA-A2-restricted CTL epitopes against hepatitis C virus induced a broadly reactive anti-HCV-specific T lymphocyte response.

PLoS ONE; 7(6) pge38390

0 2012

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Qi, Y

The acute environment, rather than T cell subset pre-commitment, regulates expression of the human T cell cytokine amphiregulin.

PLoS ONE; 7(6) pge39072

0 2012

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Forget, M

Stimulation of Wnt/ÃŸ-catenin pathway in human CD8+ T lymphocytes from blood and lung tumors leads to a shared young/memory phenotype.

PLoS ONE; 7(7) pge41074

0 2012

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Yang, Z

Combined therapy with cytokine-induced killer cells and oncolytic adenovirus expressing IL-12 induce enhanced antitumor activity in liver tumor model.

PLoS ONE; 7(9) pge44802

0 2012

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Dolganiuc, A

Type III interferons, IL-28 and IL-29, are increased in chronic HCV infection and induce myeloid dendritic cell-mediated FoxP3+ regulatory T cells.

PLoS ONE; 7(10) pge44915

0 2012

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Testa, J S

MHC class I-presented T cell epitopes identified by immunoproteomics analysis are targets for a cross reactive influenza-specific T cell response.

PLoS ONE; 7(11) pge48484

0 2012

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Domaica, C I

Human natural killer cell maturation defect supports in vivo CD56(bright) to CD56(dim) lineage development.

PLoS ONE; 7(12) pge51677

0 2012

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Zhang, Q

Suppression of natural killer cells by sorafenib contributes to prometastatic effects in hepatocellular carcinoma.

PLoS ONE; 8(2) pge55945

0 2013

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Du, W

Foxp3+ Treg expanded from patients with established diabetes reduce Helios expression while retaining normal function compared to healthy individuals.

PLoS ONE; 8(2) pge56209

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Portevin, D

Natural killer cell cytokine response to M. bovis BCG Is associated with inhibited proliferation, increased apoptosis and ultimate depletion of NKp44(+)CD56(bright) cells.

PLoS ONE; 8(7) pge68864

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Saïdi, H

HMGB1-dependent triggering of HIV-1 replication and persistence in dendritic cells as a consequence of NK-DC cross-talk.

PLoS ONE; 3(10) pge3601

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Wälchli, S

A practical approach to T-cell receptor cloning and expression.

PLoS ONE; 6(11) pge27930

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Authentication of primordial characteristics of the CLBL-1 cell line prove the integrity of a canine B-cell lymphoma in a murine in vivo model.

PLoS ONE; 7(6) pge40078

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Sørensen, R B

The immune system strikes back: cellular immune responses against indoleamine 2,3-dioxygenase.

PLoS ONE; 4(9) pge6910

7 Sep 2009

19738905
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Rütgen, B C

Authentication of primordial characteristics of the CLBL-1 cell line prove the integrity of a canine B-cell lymphoma in a murine in vivo model.

PLoS ONE; 7(6) pge40078

0 2012

22761949
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Sørensen, R B

The immune system strikes back: cellular immune responses against indoleamine 2,3-dioxygenase.

PLoS ONE; 4(9) pge6910

7 Sep 2009

19738905
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Saïdi, H

HMGB1-dependent triggering of HIV-1 replication and persistence in dendritic cells as a consequence of NK-DC cross-talk.

PLoS ONE; 3(10) pge3601

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Wälchli, S

A practical approach to T-cell receptor cloning and expression.

PLoS ONE; 6(11) pge27930

0 2011

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Enose-Akahata, Y

High expression of CD244 and SAP regulated CD8 T cell responses of patients with HTLV-I associated neurologic disease.

PLoS Pathogens; 5(12) pge1000682

0 Dec 2009

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Melki, M

Escape of HIV-1-infected dendritic cells from TRAIL-mediated NK cell cytotoxicity during NK-DC cross-talk--a pivotal role of HMGB1.

PLoS Pathogens; 6(4) pge1000862

15 Apr 2010

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Pido-Lopez, J

Acquisition of pneumococci specific effector and regulatory Cd4+ T cells localising within human upper respiratory-tract mucosal lymphoid tissue.

PLoS Pathogens; 7(12) pge1002396

0 Dec 2011

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Huang, Y

Relatively low level of antigen-specific monocytes detected in blood from untreated tuberculosis patients using CD4+ T-cell receptor tetramers.

PLoS Pathogens; 8(11) pge1003036

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Bedard, M

Sterile activation of invariant natural killer T cells by ER-stressed antigen-presenting cells.

Proceedings of the National Academy of Sciences of the USA; 116(47) pg23671-23681

19 Nov 2019

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Gibellini, D

HIV-1 and recombinant gp120 affect the survival and differentiation of human vessel wall-derived mesenchymal stem cells.

Retrovirology; 8 pg40

25 May 2011

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Meuwissen, P J

Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function.

Retrovirology; 9 pg34

27 Apr 2012

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Bonnet, A

Low nuclear body formation and tax SUMOylation do not prevent NF-kappaB promoter activation.

Retrovirology; 9 pg77

25 Sep 2012

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Daszkiewicz, L

Distinct p21 requirements for regulating normal and self-reactive T cells through IFN-Î³ production.

Scientific Reports; 5 pg7691

9 Jan 2015

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Ni, F

MicroRNA transcriptomes of distinct human NK cell populations identify miR-362-5p as an essential regulator of NK cell function.

Scientific Reports; 5 pg9993

24 Apr 2015

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Scoville, S D

Rapid Column-Free Enrichment of Mononuclear Cells from Solid Tissues.

Scientific Reports; 5 pg12490

30 Jul 2015

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Rovituso, D M

The brain antigen-specific B cell response correlates with glatiramer acetate responsiveness in relapsing-remitting multiple sclerosis patients.

Scientific Reports; 5 pg14265

21 Sep 2015

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Mailer, R K

IL-1Î² promotes Th17 differentiation by inducing alternative splicing of FOXP3.

Scientific Reports; 5 pg14674

6 Oct 2015

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Pink, D

High efficacy vasopermeability drug candidates identified by screening in an ex ovo chorioallantoic membrane model.

Scientific Reports; 5 pg15756

29 Oct 2015

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Zhang, Z

Epigenetic regulation of NKG2D ligands is involved in exacerbated atherosclerosis development in Sirt6 heterozygous mice.

Scientific Reports; 6 pg23912

5 Apr 2016

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Kim, H

Inhibition of HIV-1 reactivation by a telomerase-derived peptide in a HSP90-dependent manner.

Scientific Reports; 6 pg28896

1 Jul 2016

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Rovituso, D M

CEACAM1 mediates B cell aggregation in central nervous system autoimmunity.

Scientific Reports; 6 pg29847

20 Jul 2016

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Wei, Y

Generation and protective efficacy of a cold-adapted attenuated avian H9N2 influenza vaccine.

Scientific Reports; 6 pg30382

26 Jul 2016

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Yu, T

MicroRNA-491 regulates the proliferation and apoptosis of CD8(+) T cells.

Scientific Reports; 6 pg30923

3 Aug 2016

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Clement, M

Targeted suppression of autoreactive CD8

Scientific Reports; 6 pg35332

17 Oct 2016

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Lee, W W

Virus infection drives IL-2 antibody complexes into pro-inflammatory agonists in mice.

Scientific Reports; 6 pg37603

25 Nov 2016

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Liaskou, E

Genetic variation at the CD28 locus and its impact on expansion of pro-inflammatory CD28 negative T cells in healthy individuals.

Scientific Reports; 7(1) pg7652

9 Aug 2017

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Yang, L

Enhancing NK cell-mediated cytotoxicity to cisplatin-resistant lung cancer cells via MEK/Erk signaling inhibition.

Scientific Reports; 7(1) pg7958

11 Aug 2017

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Speir, M

Glycolipid-peptide conjugate vaccines enhance CD8

Scientific Reports; 7(1) pg14273

27 Oct 2017

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Hong, C

Circulating exosomes carrying an immunosuppressive cargo interfere with cellular immunotherapy in acute myeloid leukemia.

Scientific Reports; 7(1) pg14684

31 Oct 2017

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Kulkarni, R

Exosomes Derived from HIV-1 Infected DCs Mediate Viral trans-Infection via Fibronectin and Galectin-3.

Scientific Reports; 7(1) pg14787

1 Nov 2017

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Lee, J

Tolerogenic dendritic cells are efficiently generated using minocycline and dexamethasone.

Scientific Reports; 7(1) pg15087

8 Nov 2017

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Chapelin, F

Fluorine-19 nuclear magnetic resonance of chimeric antigen receptor T cell biodistribution in murine cancer model.

Scientific Reports; 7(1) pg17748

18 Dec 2017

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Zhong, H

Whole transcriptome profiling reveals major cell types in the cellular immune response against acute and chronic active Epstein-Barr virus infection.

Scientific Reports; 7(1) pg17775

19 Dec 2017

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Gherardin, N A

Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma.

Scientific Reports; 8(1) pg4159

7 Mar 2018

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Zhang, C

Genetic abrogation of immune checkpoints in antigen-specific cytotoxic T-lymphocyte as a potential alternative to blockade immunotherapy.

Scientific Reports; 8(1) pg5549

3 Apr 2018

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Majumder, S

A cancer vaccine approach for personalized treatment of Lynch Syndrome.

Scientific Reports; 8(1) pg12122

14 Aug 2018

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Abrahamsen, G

Polarity of CD4+ T cells towards the antigen presenting cell is regulated by the Lck adapter TSAd.

Scientific Reports; 8(1) pg13319

6 Sep 2018

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Sharma, R K

Diminished TLR2-TLR9 mediated CD4+ T cell responses are associated with increased inflammation in intraocular tuberculosis.

Scientific Reports; 8(1) pg13812

14 Sep 2018

30218032
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Lee, W J

IFITM proteins inhibit HIV-1 protein synthesis.

Scientific Reports; 8(1) pg14551

28 Sep 2018

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Vasko, T

Telomerase gene expression bioassays indicate metabolic activation of genotoxic lower chlorinated polychlorinated biphenyls.

Scientific Reports; 8(1) pg16903

15 Nov 2018

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Brey, C U

A gB/CD3 bispecific BiTE antibody construct for targeting Human Cytomegalovirus-infected cells.

Scientific Reports; 8(1) pg17453

28 Nov 2018

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Vahedi, F

Ex Vivo Expanded Human NK Cells Survive and Proliferate in Humanized Mice with Autologous Human Immune Cells.

Scientific Reports; 7(1) pg12083

21 Sep 2017

28935883
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Björkander, S

Staphylococcus aureus-derived factors induce IL-10, IFN-γ and IL-17A-expressing FOXP3+CD161+ T-helper cells in a partly monocyte-dependent manner.

Scientific Reports; 6 pg22083

26 Feb 2016

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Björkander, S

Staphylococcus aureus-derived factors induce IL-10, IFN-γ and IL-17A-expressing FOXP3+CD161+ T-helper cells in a partly monocyte-dependent manner.

Scientific Reports; 6 pg22083

26 Feb 2016

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Kasprowicz, R

A correlative and quantitative imaging approach enabling characterization of primary cell-cell communication: Case of human CD4

Scientific Reports; 8(1) pg8003

22 May 2018

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Jarrell, J A

Intracellular delivery of mRNA to human primary T cells with microfluidic vortex shedding.

Scientific Reports; 9(1) pg3214

1 Mar 2019

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Sarkar, B

Degradation of p47 by autophagy contributes to CADM1 overexpression in ATLL cells through the activation of NF-κB.

Scientific Reports; 9(1) pg3491

5 Mar 2019

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Jiang, L

Continuous targeted kinase inhibitors treatment induces upregulation of PD-L1 in resistant NSCLC.

Scientific Reports; 9(1) pg3705

6 Mar 2019

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Stakheev, D

The WNT/β-catenin signaling inhibitor XAV939 enhances the elimination of LNCaP and PC-3 prostate cancer cells by prostate cancer patient lymphocytes in vitro.

Scientific Reports; 9(1) pg4761

18 Mar 2019

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Prasad, A

Methamphetamine functions as a novel CD4

Scientific Reports; 9(1) pg958

30 Jan 2019

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Vautrin, A

Both anti-inflammatory and antiviral properties of novel drug candidate ABX464 are mediated by modulation of RNA splicing.

Scientific Reports; 9(1) pg792

28 Jan 2019

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van der Waals, L

Differential anti-tumour effects of MTH1 inhibitors in patient-derived 3D colorectal cancer cultures.

Scientific Reports; 9(1) pg819

28 Jan 2019

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Yamin, R

High percentages and activity of synovial fluid NK cells present in patients with advanced stage active Rheumatoid Arthritis.

Scientific Reports; 9(1) pg1351

4 Feb 2019

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Mesquitta, W

UM171 expands distinct types of myeloid and NK progenitors from human pluripotent stem cells.

Scientific Reports; 9(1) pg6622

29 Apr 2019

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Reijnders, T D

Unraveling the identity of FoxP3+ regulatory T cells in Granulomatosis with Polyangiitis patients.

Scientific Reports; 9(1) pg8273

4 Jun 2019

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Taouk, G

CD56 expression in breast cancer induces sensitivity to natural killer-mediated cytotoxicity by enhancing the formation of cytotoxic immunological synapse.

Scientific Reports; 9(1) pg8756

19 Jun 2019

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Nyanhete, T E

HLA class II-Restricted CD8+ T cells in HIV-1 Virus Controllers.

Scientific Reports; 9(1) pg10165

15 Jul 2019

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Figueiredo, C

Low immunogenic endothelial cells endothelialize the Left Ventricular Assist Device.

Scientific Reports; 9(1) pg11318

5 Aug 2019

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Fierle, J

Integrating SpyCatcher/SpyTag covalent fusion technology into phage display workflows for rapid antibody discovery.

Scientific Reports; 9(1) pg12815

6 Sep 2019

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Bonne-Année, S

Differential Modulation of Human Innate Lymphoid Cell (ILC) Subsets by IL-10 and TGF-β

Scientific Reports; 9 (1), 1430

4 Oct 2019

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Elmetwali, T

CD40L membrane retention enhances the immunostimulatory effects of CD40 ligation.

Scientific Reports; 10(1) pg342

15 Jan 2020

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GSK3Î² Inhibition Promotes Efficient Myeloid and Lymphoid Hematopoiesis from Non-human Primate-Induced Pluripotent Stem Cells.

Stem Cell Reports; 6(2) pg243-56

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Generation of "Off-the-Shelf" Natural Killer Cells from Peripheral Blood Cell-Derived Induced Pluripotent Stem Cells.

Stem Cell Reports; 9(6) pg1796-1812

12 Dec 2017

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Artrip, J H

Target cell susceptibility to lysis by human natural killer cells is augmented by alpha(1,3)-galactosyltransferase and reduced by alpha(1, 2)-fucosyltransferase.

The Journal of Biological Chemistry; 274(16) pg10717-22

16 Apr 1999

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Three loops of the common gamma chain ectodomain required for the binding of interleukin-2 and interleukin-7.

The Journal of Biological Chemistry; 275(39) pg30100-5

29 Sep 2000

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Identification of amino acid residues critical for biological activity in human interleukin-18.

The Journal of Biological Chemistry; 277(13) pg10998-1003

29 Mar 2002

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Structural basis for binding multiple ligands by the common cytokine receptor gamma-chain.

The Journal of Biological Chemistry; 277(14) pg12047-52

5 Apr 2002

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Physical and functional interactions between STAP-2/BKS and STAT5.

The Journal of Biological Chemistry; 280(9) pg8188-96

4 Mar 2005

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Phosphatidylinositol 3-kinase-dependent modulation of carnitine palmitoyltransferase 1A expression regulates lipid metabolism during hematopoietic cell growth.

The Journal of Biological Chemistry; 281(49) pg37372-80

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Matrix metalloproteinase processing of CXCL11/I-TAC results in loss of chemoattractant activity and altered glycosaminoglycan binding.

The Journal of Biological Chemistry; 283(28) pg19389-99

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Innate immune signaling induces high levels of TC-specific deaminase activity in primary monocyte-derived cells through expression of APOBEC3A isoforms.

The Journal of Biological Chemistry; 285(36) pg27753-66

3 Sep 2010

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CC chemokine receptor 5 (CCR5) desensitization: cycling receptors accumulate in the trans-Golgi network.

The Journal of Biological Chemistry; 285(53) pg41772-80

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Sts-2 is a phosphatase that negatively regulates zeta-associated protein (ZAP)-70 and T cell receptor signaling pathways.

The Journal of Biological Chemistry; 286(18) pg15943-54

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Role of runt-related transcription factor 3 (RUNX3) in transcription regulation of natural cytotoxicity receptor 1 (NCR1/NKp46), an activating natural killer (NK) cell receptor.

The Journal of Biological Chemistry; 287(10) pg7324-34

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Anticancer drugs cause release of exosomes with heat shock proteins from human hepatocellular carcinoma cells that elicit effective natural killer cell antitumor responses in vitro.

The Journal of Biological Chemistry; 287(19) pg15874-85

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Tax protein-induced expression of antiapoptotic Bfl-1 protein contributes to survival of human T-cell leukemia virus type 1 (HTLV-1)-infected T-cells.

The Journal of Biological Chemistry; 287(25) pg21357-70

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Leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction induces a novel genetic signature resulting in T-cells refractory to transforming growth factor-Î² signaling.

The Journal of Biological Chemistry; 287(32) pg27204-16

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T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting.

The Journal of Biological Chemistry; 287(44) pg37269-81

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Human and mouse type I natural killer T cell antigen receptors exhibit different fine specificities for CD1d-antigen complex.

The Journal of Biological Chemistry; 287(46) pg39139-48

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T cell receptor (TCR) and transforming growth factor Î² (TGF-Î²) signaling converge on DNA (cytosine-5)-methyltransferase to control forkhead box protein 3 (foxp3) locus methylation and inducible regulatory T cell differentiation.

The Journal of Biological Chemistry; 288(26) pg19127-39

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Phosphorylation of Rab5a protein by protein kinase CÏµ is crucial for T-cell migration.

The Journal of Biological Chemistry; 289(28) pg19420-34

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Induced expression of FcÎ³RIIIa (CD16a) on CD4+ T cells triggers generation of IFN-Î³high subset.

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MicroRNA-155 Reinforces HIV Latency.

The Journal of Biological Chemistry; 290(22) pg13736-48

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Targeting the binding interface on a shared receptor subunit of a cytokine family enables the inhibition of multiple member cytokines with selectable target spectrum.

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Nicotinic Acid Adenine Dinucleotide Phosphate Plays a Critical Role in Naive and Effector Murine T Cells but Not Natural Regulatory T Cells.

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Li, X

Tumor Progression Locus 2 (Tpl2) Activates the Mammalian Target of Rapamycin (mTOR) Pathway, Inhibits Forkhead Box P3 (FoxP3) Expression, and Limits Regulatory T Cell (Treg) Immunosuppressive Functions.

The Journal of Biological Chemistry; 291(32) pg16802-15

5 Aug 2016

27261457
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Lykken, E A

The MicroRNA miR-191 Supports T Cell Survival Following Common Î³ Chain Signaling.

The Journal of Biological Chemistry; 291(45) pg23532-23544

4 Nov 2016

27634043
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Akhter, N

Apurinic/Apyrimidinic Endonuclease 1/Redox Factor-1 (Ape1/Ref-1) Modulates Antigen Presenting Cell-mediated T Helper Cell Type 1 Responses.

The Journal of Biological Chemistry; 291(45) pg23672-23680

4 Nov 2016

27637330
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Cole, D K

Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.

The Journal of Biological Chemistry; 292(3) pg802-813

20 Jan 2017

27903649
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Shams, K

MicroRNA-146 and cell trauma down-regulate expression of the psoriasis-associated atypical chemokine receptor ACKR2.

The Journal of Biological Chemistry; 293(8) pg3003-3012

23 Feb 2018

29279330
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Müller, J R

Paracrine and transpresentation functions of IL-15 are mediated by diverse splice versions of IL-15Rα in human monocytes and dendritic cells.

The Journal of Biological Chemistry; 287(48) pg40328-38

23 Nov 2012

23074221
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Müller, J R

Paracrine and transpresentation functions of IL-15 are mediated by diverse splice versions of IL-15Rα in human monocytes and dendritic cells.

The Journal of Biological Chemistry; 287(48) pg40328-38

23 Nov 2012

23074221
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Meng, M

A dynamic transcriptomic atlas of cytokine-induced killer cells.

The Journal of Biological Chemistry; 293(51) pg19600-19612

21 Dec 2018

30333226
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Tirumuru, N

HIV-1 envelope proteins up-regulate

The Journal of Biological Chemistry; 294(9) pg3249-3260

1 Mar 2019

30617182
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Zhang, Y

Membrane-associated RING-CH (MARCH) 1 and 2 are MARCH family members that inhibit HIV-1 infection.

The Journal of Biological Chemistry; 294(10) pg3397-3405

8 Mar 2019

30630952
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Coorens, M

Innate lymphoid cell type 3-derived interleukin-22 boosts lipocalin-2 production in intestinal epithelial cells via synergy between STAT3 and NF-κB.

The Journal of Biological Chemistry; 294(15) pg6027-6041

12 Apr 2019

30782844
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Lee, A W

A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.

The Journal of Biological Chemistry; 294(29) pg11199-11212

19 Jul 2019

31167786
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De Wit, F

Design of reverse transcriptase-specific nucleosides to visualize early steps of HIV-1 replication by click labeling.

The Journal of Biological Chemistry; 294(31) pg11863-11875

2 Aug 2019

31201270
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Gérard, A

The Par polarity complex regulates Rap1- and chemokine-induced T cell polarization.

The Journal of Cell Biology; 176(6) pg863-75

12 Mar 2007

17353362
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Gérard, A

The Par polarity complex regulates Rap1- and chemokine-induced T cell polarization.

The Journal of Cell Biology; 176(6) pg863-75

12 Mar 2007

17353362
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Pugh-Bernard, A E

Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance.

The Journal of Clinical Investigation; 108(7) pg1061-70

0 Oct 2001

11581307
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Kita, H

Quantitative and functional analysis of PDC-E2-specific autoreactive cytotoxic T lymphocytes in primary biliary cirrhosis.

The Journal of Clinical Investigation; 109(9) pg1231-40

0 May 2002

11994412
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Malmberg, K

IFN-gamma protects short-term ovarian carcinoma cell lines from CTL lysis via a CD94/NKG2A-dependent mechanism.

The Journal of Clinical Investigation; 110(10) pg1515-23

0 Nov 2002

12438449
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Courtois, G

A hypermorphic IkappaBalpha mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodeficiency.

The Journal of Clinical Investigation; 112(7) pg1108-15

0 Oct 2003

14523047
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Wu, J D

Prevalent expression of the immunostimulatory MHC class I chain-related molecule is counteracted by shedding in prostate cancer.

The Journal of Clinical Investigation; 114(4) pg560-8

0 Aug 2004

15314693
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Kaufman, H L

Targeting the local tumor microenvironment with vaccinia virus expressing B7.1 for the treatment of melanoma.

The Journal of Clinical Investigation; 115(7) pg1903-12

0 Jul 2005

15937544
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Song, L

Oncogene MYCN regulates localization of NKT cells to the site of disease in neuroblastoma.

The Journal of Clinical Investigation; 117(9) pg2702-12

0 Sep 2007

17710228
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Balabanian, K

Leukocyte analysis from WHIM syndrome patients reveals a pivotal role for GRK3 in CXCR4 signaling.

The Journal of Clinical Investigation; 118(3) pg1074-84

0 Mar 2008

18274673
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Song, L

Valpha24-invariant NKT cells mediate antitumor activity via killing of tumor-associated macrophages.

The Journal of Clinical Investigation; 119(6) pg1524-36

0 Jun 2009

19411762
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Snow, A L

Restimulation-induced apoptosis of T cells is impaired in patients with X-linked lymphoproliferative disease caused by SAP deficiency.

The Journal of Clinical Investigation; 119(10) pg2976-89

0 Oct 2009

19759517
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Liu, D

IL-15 protects NKT cells from inhibition by tumor-associated macrophages and enhances antimetastatic activity.

The Journal of Clinical Investigation; 122(6) pg2221-33

0 Jun 2012

22565311
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Henson, S M

p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8âº T cells.

The Journal of Clinical Investigation; 124(9) pg4004-16

0 Sep 2014

25083993
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Kenefeck, R

Follicular helper T cell signature in type 1 diabetes.

The Journal of Clinical Investigation; 125(1) pg292-303

0 Jan 2015

25485678
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McCracken, M N

Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging.

The Journal of Clinical Investigation; 125(5) pg1815-26

0 May 2015

25822024
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Chauvin, J

TIGIT and PD-1 impair tumor antigen-specific CD8âº T cells in melanoma patients.

The Journal of Clinical Investigation; 125(5) pg2046-58

0 May 2015

25866972
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Zhang, Z

Plasmacytoid dendritic cells promote HIV-1-induced group 3 innate lymphoid cell depletion.

The Journal of Clinical Investigation; 125(9) pg3692-703

0 Sep 2015

26301812
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Quast, I

Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity.

The Journal of Clinical Investigation; 125(11) pg4160-70

2 Nov 2015

26436649
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Ohmura, S

Lineage-affiliated transcription factors bind the Gata3 Tce1 enhancer to mediate lineage-specific programs.

The Journal of Clinical Investigation; 126(3) pg865-78

1 Mar 2016

26808502
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Kupz, A

ESAT-6-dependent cytosolic pattern recognition drives noncognate tuberculosis control in vivo.

The Journal of Clinical Investigation; 126(6) pg2109-22

1 Jun 2016

27111234
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Kagoya, Y

BET bromodomain inhibition enhances T cell persistence and function in adoptive immunotherapy models.

The Journal of Clinical Investigation; 126(9) pg3479-94

1 Sep 2016

27548527
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Cantaert, T

Decreased somatic hypermutation induces an impaired peripheral B cell tolerance checkpoint.

The Journal of Clinical Investigation; 126(11) pg4289-4302

1 Nov 2016

27701145
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Wu, R

MicroRNA-210 overexpression promotes psoriasis-like inflammation by inducing Th1 and Th17 cell differentiation.

The Journal of Clinical Investigation; 128(6) pg2551-2568

1 Jun 2018

29757188
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Mathews, D V

CD122 signaling in CD8+ memory T cells drives costimulation-independent rejection.

The Journal of Clinical Investigation; 128(10) pg4557-4572

1 Oct 2018

30222140
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Côte, M

Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells.

The Journal of Clinical Investigation; 119(12) pg3765-73

0 Dec 2009

19884660
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Brüstle, A

The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells.

The Journal of Clinical Investigation; 122(12) pg4698-709

0 Dec 2012

23114599
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Bécart, S

SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca2+/NFAT signaling.

The Journal of Clinical Investigation; 117(8) pg2164-75

0 Aug 2007

17657315
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Brüstle, A

The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells.

The Journal of Clinical Investigation; 122(12) pg4698-709

0 Dec 2012

23114599
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Bécart, S

SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca2+/NFAT signaling.

The Journal of Clinical Investigation; 117(8) pg2164-75

0 Aug 2007

17657315
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Côte, M

Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells.

The Journal of Clinical Investigation; 119(12) pg3765-73

0 Dec 2009

19884660
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Chen, F

Neoantigen identification strategies enable personalized immunotherapy in refractory solid tumors.

The Journal of Clinical Investigation; 130

5 Mar 2019

30835255
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Xu, Y

Tumor suppressor TET2 promotes cancer immunity and immunotherapy efficacy.

The Journal of Clinical Investigation; 130 pg4316-4331

16 Jul 2019

31310587
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Mathew, A

Signal transducer and activator of transcription 6 controls chemokine production and T helper cell type 2 cell trafficking in allergic pulmonary inflammation.

The Journal of Experimental Medicine; 193(9) pg1087-96

7 May 2001

11342593
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Piccirillo, C A

CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness.

The Journal of Experimental Medicine; 196(2) pg237-46

15 Jul 2002

12119348
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Gorska, M M

Unc119, a novel activator of Lck/Fyn, is essential for T cell activation.

The Journal of Experimental Medicine; 199(3) pg369-79

2 Feb 2004

14757743
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Lin, L

Active inhibition of plasma cell development in resting B cells by microphthalmia-associated transcription factor.

The Journal of Experimental Medicine; 200(1) pg115-22

5 Jul 2004

15226356
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Bai, X

CD24 controls expansion and persistence of autoreactive T cells in the central nervous system during experimental autoimmune encephalomyelitis.

The Journal of Experimental Medicine; 200(4) pg447-58

16 Aug 2004

15314074
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Benz, C

A multipotent precursor in the thymus maps to the branching point of the T versus B lineage decision.

The Journal of Experimental Medicine; 202(1) pg21-31

4 Jul 2005

15983065
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Kuo, T C

Repression of BCL-6 is required for the formation of human memory B cells in vitro.

The Journal of Experimental Medicine; 204(4) pg819-30

16 Apr 2007

17403935
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Griseri, T

OX40 is required for regulatory T cell-mediated control of colitis.

The Journal of Experimental Medicine; 207(4) pg699-709

12 Apr 2010

20368580
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Gottschalk, R A

TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo.

The Journal of Experimental Medicine; 207(8) pg1701-11

2 Aug 2010

20660617
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Sundling, C

Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates.

The Journal of Experimental Medicine; 207(9) pg2003-17

30 Aug 2010

20679401
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Fourcade, J

Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients.

The Journal of Experimental Medicine; 207(10) pg2175-86

27 Sep 2010

20819923
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Wang, L

VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses.

The Journal of Experimental Medicine; 208(3) pg577-92

14 Mar 2011

21383057
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Weiss, J M

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells.

The Journal of Experimental Medicine; 209(10) pg1723-42, S1

24 Sep 2012

22966001
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Snow, A L

Congenital B cell lymphocytosis explained by novel germline CARD11 mutations.

The Journal of Experimental Medicine; 209(12) pg2247-61

19 Nov 2012

23129749
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Pachlopnik Schmid, J

Polymerase Îµ1 mutation in a human syndrome with facial dysmorphism, immunodeficiency, livedo, and short stature ("FILS syndrome").

The Journal of Experimental Medicine; 209(13) pg2323-30

17 Dec 2012

23230001
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Kotlarz, D

Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome.

The Journal of Experimental Medicine; 210(3) pg433-43

11 Mar 2013

23440042
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Wang, C

BATF is required for normal expression of gut-homing receptors by T helper cells in response to retinoic acid.

The Journal of Experimental Medicine; 210(3) pg475-89

11 Mar 2013

23460729
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Gasteiger, G

IL-2-dependent tuning of NK cell sensitivity for target cells is controlled by regulatory T cells.

The Journal of Experimental Medicine; 210(6) pg1167-78

3 Jun 2013

23650441
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Weber, G F

Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis.

The Journal of Experimental Medicine; 211(6) pg1243-56

2 Jun 2014

24821911
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Cichocki, F

Transcriptional regulation of Munc13-4 expression in cytotoxic lymphocytes is disrupted by an intronic mutation associated with a primary immunodeficiency.

The Journal of Experimental Medicine; 211(6) pg1079-91

2 Jun 2014

24842371
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Bourgeois, E A

Bee venom processes human skin lipids for presentation by CD1a.

The Journal of Experimental Medicine; 212(2) pg149-63

9 Feb 2015

25584012
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Jenkins, M R

Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time.

The Journal of Experimental Medicine; 212(3) pg307-17

9 Mar 2015

25732304
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Lim, H W

SIRT1 deacetylates RORÎ³t and enhances Th17 cell generation.

The Journal of Experimental Medicine; 212(5) pg607-17

4 May 2015

25918343
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Frye, M

Interfering with VE-PTP stabilizes endothelial junctions in vivo via Tie-2 in the absence of VE-cadherin.

The Journal of Experimental Medicine; 212(13) pg2267-87

14 Dec 2015

26642851
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Yue, X

Control of Foxp3 stability through modulation of TET activity.

The Journal of Experimental Medicine; 213(3) pg377-97

7 Mar 2016

26903244
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Liu, W

A miR-155-Peli1-c-Rel pathway controls the generation and function of T follicular helper cells.

The Journal of Experimental Medicine; 213(9) pg1901-19

22 Aug 2016

27481129
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Chopra, M

Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion.

The Journal of Experimental Medicine; 213(9) pg1881-900

22 Aug 2016

27526711
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Cheung, K L

Psoriatic T cells recognize neolipid antigens generated by mast cell phospholipase delivered by exosomes and presented by CD1a.

The Journal of Experimental Medicine; 213(11) pg2399-2412

17 Oct 2016

27670592
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Abolhassani, H

Combined immunodeficiency and Epstein-Barr virus-induced B cell malignancy in humans with inherited CD70 deficiency.

The Journal of Experimental Medicine; 214(1) pg91-106

0 Jan 2017

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Lyons, J J

ERBIN deficiency links STAT3 and TGF-Î² pathway defects with atopy in humans.

The Journal of Experimental Medicine; 214(3) pg669-680

6 Mar 2017

28126831
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Chheda, Z S

Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy.

The Journal of Experimental Medicine; 215(1) pg141-157

2 Jan 2018

29203539
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Yu, F

The transcription factor Bhlhe40 is a switch of inflammatory versus antiinflammatory Th1 cell fate determination.

The Journal of Experimental Medicine; 215(7) pg1813-1821

2 Jul 2018

29773643
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Brummelman, J

High-dimensional single cell analysis identifies stem-like cytotoxic CD8

The Journal of Experimental Medicine; 215(10) pg2520-2535

1 Oct 2018

30154266
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Sawada, S

Disturbed CD4+ T cell homeostasis and in vitro HIV-1 susceptibility in transgenic mice expressing T cell line-tropic HIV-1 receptors.

The Journal of Experimental Medicine; 187(9) pg1439-49

4 May 1998

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Thornton, A M

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production.

The Journal of Experimental Medicine; 188(2) pg287-96

20 Jul 1998

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Imada, K

Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity.

The Journal of Experimental Medicine; 188(11) pg2067-74

7 Dec 1998

9841920
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Michaëlsson, J

A signal peptide derived from hsp60 binds HLA-E and interferes with CD94/NKG2A recognition.

The Journal of Experimental Medicine; 196(11) pg1403-14

2 Dec 2002

12461076
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Michaëlsson, J

A signal peptide derived from hsp60 binds HLA-E and interferes with CD94/NKG2A recognition.

The Journal of Experimental Medicine; 196(11) pg1403-14

2 Dec 2002

12461076
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Zhang, Z

Human interleukin-2 receptor β mutations associated with defects in immunity and peripheral tolerance.

The Journal of Experimental Medicine; 216(6) pg1311-1327

3 Jun 2019

31040185
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Zhu, Y

The E3 ligase VHL promotes follicular helper T cell differentiation via glycolytic-epigenetic control.

The Journal of Experimental Medicine; 216(7) pg1664-1681

1 Jul 2019

31123085
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Prager, I

NK cells switch from granzyme B to death receptor-mediated cytotoxicity during serial killing.

The Journal of Experimental Medicine; 216(9) pg2113-2127

2 Sep 2019

31270246
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Sugiura, K

Construction of an expression vector for improved secretion of canine IL-18.

Veterinary Immunology and Immunopathology; 126(3-4) pg388-91

15 Dec 2008

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Liu, Y Z

Pegylated interferon Î± enhances recovery of memory T cells in e antigen positive chronic hepatitis B patients.

Virology Journal; 9 pg274

16 Nov 2012

23158844
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Wang, D

A CD8 T cell/indoleamine 2,3-dioxygenase axis is required for mesenchymal stem cell suppression of human systemic lupus erythematosus.

Arthritis and Rheumatology; 66(8) pg2234-45

1 Aug 2014

24756936
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Yan, F

Human dental pulp stem cells regulate allogeneic NK cells' function via induction of anti-inflammatory purinergic signalling in activated NK cells.

Cell Proliferation; 52(3) pge12595

1 May 2019

30953394
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Chi, X

Significantly increased anti-tumor activity of carcinoembryonic antigen-specific chimeric antigen receptor T cells in combination with recombinant human IL-12.

Cancer Medicine; 8(10) pg4753-4765

1 Aug 2019

31237116
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Perera, L P

IL-15 induces the expression of chemokines and their receptors in T lymphocytes.

Journal of immunology (Baltimore, Md. : 1950); 162(5) pg2606-12

1 Mar 1999

10072502
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Jinquan, T

Eotaxin activates T cells to chemotaxis and adhesion only if induced to express CCR3 by IL-2 together with IL-4.

Journal of immunology (Baltimore, Md. : 1950); 162(7) pg4285-92

1 Apr 1999

10201960
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Sato, K

Aberrant CD3- and CD28-mediated signaling events in cord blood T cells are associated with dysfunctional regulation of Fas ligand-mediated cytotoxicity.

Journal of immunology (Baltimore, Md. : 1950); 162(8) pg4464-71

15 Apr 1999

10201983
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Nibbs, R J

C-C chemokine receptor 3 antagonism by the beta-chemokine macrophage inflammatory protein 4, a property strongly enhanced by an amino-terminal alanine-methionine swap.

Journal of immunology (Baltimore, Md. : 1950); 164(3) pg1488-97

1 Feb 2000

10640766
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Sauty, A

CXCR3 internalization following T cell-endothelial cell contact: preferential role of IFN-inducible T cell alpha chemoattractant (CXCL11).

Journal of immunology (Baltimore, Md. : 1950); 167(12) pg7084-93

15 Dec 2001

11739530
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Kinter, A L

HIV envelope induces virus expression from resting CD4+ T cells isolated from HIV-infected individuals in the absence of markers of cellular activation or apoptosis.

Journal of immunology (Baltimore, Md. : 1950); 170(5) pg2449-55

1 Mar 2003

12594269
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Takaki, T

Requirement for both H-2Db and H-2Kd for the induction of diabetes by the promiscuous CD8+ T cell clonotype AI4.

Journal of immunology (Baltimore, Md. : 1950); 173(4) pg2530-41

15 Aug 2004

15294969
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Curnow, S J

Inhibition of T cell apoptosis in the aqueous humor of patients with uveitis by IL-6/soluble IL-6 receptor trans-signaling.

Journal of immunology (Baltimore, Md. : 1950); 173(8) pg5290-7

15 Oct 2004

15470075
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Lieberman, S M

Individual nonobese diabetic mice exhibit unique patterns of CD8+ T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia myotonica kinase.

Journal of immunology (Baltimore, Md. : 1950); 173(11) pg6727-34

1 Dec 2004

15557165
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Vosshenrich, C A

Roles for common cytokine receptor gamma-chain-dependent cytokines in the generation, differentiation, and maturation of NK cell precursors and peripheral NK cells in vivo.

Journal of immunology (Baltimore, Md. : 1950); 174(3) pg1213-21

1 Feb 2005

15661875
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van Beek, J

Decay-accelerating factor (CD55) is expressed by neurons in response to chronic but not acute autoimmune central nervous system inflammation associated with complement activation.

Journal of immunology (Baltimore, Md. : 1950); 174(4) pg2353-65

15 Feb 2005

15699172
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Smith, S S

Transgenic Ly-49A inhibits antigen-driven T cell activation and delays diabetes.

Journal of immunology (Baltimore, Md. : 1950); 174(7) pg3897-905

1 Apr 2005

15778344
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Mo, R

Estrogen regulates CCR gene expression and function in T lymphocytes.

Journal of immunology (Baltimore, Md. : 1950); 174(10) pg6023-9

15 May 2005

15879095
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Hedges, J F

Gamma delta T cells respond directly to pathogen-associated molecular patterns.

Journal of immunology (Baltimore, Md. : 1950); 174(10) pg6045-53

15 May 2005

15879098
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Zocchi, M R

Pertussis toxin (PTX) B subunit and the nontoxic PTX mutant PT9K/129G inhibit Tat-induced TGF-beta production by NK cells and TGF-beta-mediated NK cell apoptosis.

Journal of immunology (Baltimore, Md. : 1950); 174(10) pg6054-61

15 May 2005

15879099
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Nakamura, H

TCR engagement increases hypoxia-inducible factor-1 alpha protein synthesis via rapamycin-sensitive pathway under hypoxic conditions in human peripheral T cells.

Journal of immunology (Baltimore, Md. : 1950); 174(12) pg7592-9

15 Jun 2005

15944259
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Chu, C

The Lyn tyrosine kinase differentially regulates dendritic cell generation and maturation.

Journal of immunology (Baltimore, Md. : 1950); 175(5) pg2880-9

1 Sep 2005

16116174
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Moran, T P

A novel viral system for generating antigen-specific T cells.

Journal of immunology (Baltimore, Md. : 1950); 175(5) pg3431-8

1 Sep 2005

16116238
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Shiratori, I

Down-regulation of basophil function by human CD200 and human herpesvirus-8 CD200.

Journal of immunology (Baltimore, Md. : 1950); 175(7) pg4441-9

1 Oct 2005

16177086
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Teixeira, L K

IFN-gamma production by CD8+ T cells depends on NFAT1 transcription factor and regulates Th differentiation.

Journal of immunology (Baltimore, Md. : 1950); 175(9) pg5931-9

1 Nov 2005

16237086
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Poggi, A

Interaction between human NK cells and bone marrow stromal cells induces NK cell triggering: role of NKp30 and NKG2D receptors.

Journal of immunology (Baltimore, Md. : 1950); 175(10) pg6352-60

15 Nov 2005

16272287
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Pelletier, N

The endoplasmic reticulum is a key component of the plasma cell death pathway.

Journal of immunology (Baltimore, Md. : 1950); 176(3) pg1340-7

1 Feb 2006

16424160
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Yu, Q

OX40 ligation of CD4+ T cells enhances virus-specific CD8+ T cell memory responses independently of IL-2 and CD4+ T regulatory cell inhibition.

Journal of immunology (Baltimore, Md. : 1950); 176(4) pg2486-95

15 Feb 2006

16456009
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Zhang, R

Human NK cells positively regulate gammadelta T cells in response to Mycobacterium tuberculosis.

Journal of immunology (Baltimore, Md. : 1950); 176(4) pg2610-6

15 Feb 2006

16456023
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Takaki, T

HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes.

Journal of immunology (Baltimore, Md. : 1950); 176(5) pg3257-65

1 Mar 2006

16493087
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Ebata, K

Immature NK cells suppress dendritic cell functions during the development of leukemia in a mouse model.

Journal of immunology (Baltimore, Md. : 1950); 176(7) pg4113-24

1 Apr 2006

16547247
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Lin, L

Coordination of NF-kappaB and NFAT antagonism by the forkhead transcription factor Foxd1.

Journal of immunology (Baltimore, Md. : 1950); 176(8) pg4793-803

15 Apr 2006

16585573
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Shimoda, M

Conditional ablation of MHC-II suggests an indirect role for MHC-II in regulatory CD4 T cell maintenance.

Journal of immunology (Baltimore, Md. : 1950); 176(11) pg6503-11

1 Jun 2006

16709807
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Munitz, A

CD48 is an allergen and IL-3-induced activation molecule on eosinophils.

Journal of immunology (Baltimore, Md. : 1950); 177(1) pg77-83

1 Jul 2006

16785501
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Kamimura, D

IL-2 in vivo activities and antitumor efficacy enhanced by an anti-IL-2 mAb.

Journal of immunology (Baltimore, Md. : 1950); 177(1) pg306-14

1 Jul 2006

16785526
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Capasso, M

Costimulation via CD55 on human CD4+ T cells mediated by CD97.

Journal of immunology (Baltimore, Md. : 1950); 177(2) pg1070-7

15 Jul 2006

16818763
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Bertholet, S

Leishmania antigens are presented to CD8+ T cells by a transporter associated with antigen processing-independent pathway in vitro and in vivo.

Journal of immunology (Baltimore, Md. : 1950); 177(6) pg3525-33

15 Sep 2006

16951311
Show Usages

Green, M R

Epigenetic regulation during B cell differentiation controls CIITA promoter accessibility.

Journal of immunology (Baltimore, Md. : 1950); 177(6) pg3865-73

15 Sep 2006

16951349
Show Usages

Wittman, V P

Antibody targeting to a class I MHC-peptide epitope promotes tumor cell death.

Journal of immunology (Baltimore, Md. : 1950); 177(6) pg4187-95

15 Sep 2006

16951384
Show Usages

Lockhart, E

IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection.

Journal of immunology (Baltimore, Md. : 1950); 177(7) pg4662-9

1 Oct 2006

16982905
Show Usages

Charvet, C

Vav1 promotes T cell cycle progression by linking TCR/CD28 costimulation to FOXO1 and p27kip1 expression.

Journal of immunology (Baltimore, Md. : 1950); 177(8) pg5024-31

15 Oct 2006

17015685
Show Usages

Maddaloni, M

Mucosal vaccine targeting improves onset of mucosal and systemic immunity to botulinum neurotoxin A.

Journal of immunology (Baltimore, Md. : 1950); 177(8) pg5524-32

15 Oct 2006

17015739
Show Usages

Ding, D

Aberrant phenotype and function of myeloid dendritic cells in systemic lupus erythematosus.

Journal of immunology (Baltimore, Md. : 1950); 177(9) pg5878-89

1 Nov 2006

17056512
Show Usages

Hong, C

CD4+ T cells in the absence of the CD8+ cytotoxic T cells are critical and sufficient for NKT cell-dependent tumor rejection.

Journal of immunology (Baltimore, Md. : 1950); 177(10) pg6747-57

15 Nov 2006

17082588
Show Usages

Ito, D

The wild-type sequence (wt) p53(25-35) peptide induces HLA-DR7 and HLA-DR11-restricted CD4+ Th cells capable of enhancing the ex vivo expansion and function of anti-wt p53(264-272) peptide CD8+ T cells.

Journal of immunology (Baltimore, Md. : 1950); 177(10) pg6795-803

15 Nov 2006

17082593
Show Usages

Yang, X

Oral vaccination with salmonella simultaneously expressing Yersinia pestis F1 and V antigens protects against bubonic and pneumonic plague.

Journal of immunology (Baltimore, Md. : 1950); 178(2) pg1059-67

15 Jan 2007

17202369
Show Usages

Forestier, C

Improved outcomes in NOD mice treated with a novel Th2 cytokine-biasing NKT cell activator.

Journal of immunology (Baltimore, Md. : 1950); 178(3) pg1415-25

1 Feb 2007

17237389
Show Usages

Davidson, T S

Cutting Edge: IL-2 is essential for TGF-beta-mediated induction of Foxp3+ T regulatory cells.

Journal of immunology (Baltimore, Md. : 1950); 178(7) pg4022-6

1 Apr 2007

17371955
Show Usages

Krawczyk, C M

Functional plasticity in memory T helper cell responses.

Journal of immunology (Baltimore, Md. : 1950); 178(7) pg4080-8

1 Apr 2007

17371962
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Zhou, R

Recognition of double-stranded RNA by TLR3 induces severe small intestinal injury in mice.

Journal of immunology (Baltimore, Md. : 1950); 178(7) pg4548-56

1 Apr 2007

17372013
Show Usages

Baatar, D

Human peripheral blood T regulatory cells (Tregs), functionally primed CCR4+ Tregs and unprimed CCR4- Tregs, regulate effector T cells using FasL.

Journal of immunology (Baltimore, Md. : 1950); 178(8) pg4891-900

15 Apr 2007

17404270
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Fluur, C

Potential role for IL-7 in Fas-mediated T cell apoptosis during HIV infection.

Journal of immunology (Baltimore, Md. : 1950); 178(8) pg5340-50

15 Apr 2007

17404319
Show Usages

Sanderson, J P

Sulfamethoxazole and its metabolite nitroso sulfamethoxazole stimulate dendritic cell costimulatory signaling.

Journal of immunology (Baltimore, Md. : 1950); 178(9) pg5533-42

1 May 2007

17442935
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Darce, J R

Divergent effects of BAFF on human memory B cell differentiation into Ig-secreting cells.

Journal of immunology (Baltimore, Md. : 1950); 178(9) pg5612-22

1 May 2007

17442944
Show Usages

Wei, C

A new population of cells lacking expression of CD27 represents a notable component of the B cell memory compartment in systemic lupus erythematosus.

Journal of immunology (Baltimore, Md. : 1950); 178(10) pg6624-33

15 May 2007

17475894
Show Usages

Taylor, K N

Induction of FoxP3+CD4+25+ regulatory T cells following hemopoietic stem cell transplantation: role of bone marrow-derived facilitating cells.

Journal of immunology (Baltimore, Md. : 1950); 179(4) pg2153-62

15 Aug 2007

17675474
Show Usages

Sakuishi, K

Invariant NKT cells biased for IL-5 production act as crucial regulators of inflammation.

Journal of immunology (Baltimore, Md. : 1950); 179(6) pg3452-62

15 Sep 2007

17785779
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DiPaolo, R J

Autoantigen-specific TGFbeta-induced Foxp3+ regulatory T cells prevent autoimmunity by inhibiting dendritic cells from activating autoreactive T cells.

Journal of immunology (Baltimore, Md. : 1950); 179(7) pg4685-93

1 Oct 2007

17878367
Show Usages

Silver, P B

Hydrodynamic vaccination with DNA encoding an immunologically privileged retinal antigen protects from autoimmunity through induction of regulatory T cells.

Journal of immunology (Baltimore, Md. : 1950); 179(8) pg5146-58

15 Oct 2007

17911600
Show Usages

Racanelli, V

Bone marrow of persistently hepatitis C virus-infected individuals accumulates memory CD8+ T cells specific for current and historical viral antigens: a study in patients with benign hematological disorders.

Journal of immunology (Baltimore, Md. : 1950); 179(8) pg5387-98

15 Oct 2007

17911625
Show Usages

Holderness, J

Select plant tannins induce IL-2Ralpha up-regulation and augment cell division in gammadelta T cells.

Journal of immunology (Baltimore, Md. : 1950); 179(10) pg6468-78

15 Nov 2007

17982035
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Mariotti, J

Ex vivo rapamycin generates apoptosis-resistant donor Th2 cells that persist in vivo and prevent hemopoietic stem cell graft rejection.

Journal of immunology (Baltimore, Md. : 1950); 180(1) pg89-105

1 Jan 2008

18097008
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Fujita, M

Inhibition of STAT3 promotes the efficacy of adoptive transfer therapy using type-1 CTLs by modulation of the immunological microenvironment in a murine intracranial glioma.

Journal of immunology (Baltimore, Md. : 1950); 180(4) pg2089-98

15 Feb 2008

18250414
Show Usages

Strauss, L

Expression of ICOS on human melanoma-infiltrating CD4+CD25highFoxp3+ T regulatory cells: implications and impact on tumor-mediated immune suppression.

Journal of immunology (Baltimore, Md. : 1950); 180(5) pg2967-80

1 Mar 2008

18292519
Show Usages

Sartorius, R

The use of filamentous bacteriophage fd to deliver MAGE-A10 or MAGE-A3 HLA-A2-restricted peptides and to induce strong antitumor CTL responses.

Journal of immunology (Baltimore, Md. : 1950); 180(6) pg3719-28

15 Mar 2008

18322177
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Waithman, J

Cutting edge: Enhanced IL-2 signaling can convert self-specific T cell response from tolerance to autoimmunity.

Journal of immunology (Baltimore, Md. : 1950); 180(9) pg5789-93

1 May 2008

18424696
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Krawczyk, C M

Th2 differentiation is unaffected by Jagged2 expression on dendritic cells.

Journal of immunology (Baltimore, Md. : 1950); 180(12) pg7931-7

15 Jun 2008

18523256
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Sasaki, K

Stat6 signaling suppresses VLA-4 expression by CD8+ T cells and limits their ability to infiltrate tumor lesions in vivo.

Journal of immunology (Baltimore, Md. : 1950); 181(1) pg104-8

1 Jul 2008

18566374
Show Usages

Chaix, J

Cutting edge: Priming of NK cells by IL-18.

Journal of immunology (Baltimore, Md. : 1950); 181(3) pg1627-31

1 Aug 2008

18641298
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Fragale, A

IFN regulatory factor-1 negatively regulates CD4+ CD25+ regulatory T cell differentiation by repressing Foxp3 expression.

Journal of immunology (Baltimore, Md. : 1950); 181(3) pg1673-82

1 Aug 2008

18641303
Show Usages

Morel, E

HLA class I molecules regulate IFN-gamma production induced in NK cells by target cells, viral products, or immature dendritic cells through the inhibitory receptor ILT2/CD85j.

Journal of immunology (Baltimore, Md. : 1950); 181(4) pg2368-81

15 Aug 2008

18684926
Show Usages

Kuang, D

Tumor-educated tolerogenic dendritic cells induce CD3epsilon down-regulation and apoptosis of T cells through oxygen-dependent pathways.

Journal of immunology (Baltimore, Md. : 1950); 181(5) pg3089-98

1 Sep 2008

18713979
Show Usages

Tsuji-Takayama, K

The production of IL-10 by human regulatory T cells is enhanced by IL-2 through a STAT5-responsive intronic enhancer in the IL-10 locus.

Journal of immunology (Baltimore, Md. : 1950); 181(6) pg3897-905

15 Sep 2008

18768844
Show Usages

Tsai, C

Galectin-1 promotes immunoglobulin production during plasma cell differentiation.

Journal of immunology (Baltimore, Md. : 1950); 181(7) pg4570-9

1 Oct 2008

18802059
Show Usages

Wesa, A K

Enhancement in specific CD8+ T cell recognition of EphA2+ tumors in vitro and in vivo after treatment with ligand agonists.

Journal of immunology (Baltimore, Md. : 1950); 181(11) pg7721-7

1 Dec 2008

19017961
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Noursadeghi, M

Genome-wide innate immune responses in HIV-1-infected macrophages are preserved despite attenuation of the NF-kappa B activation pathway.

Journal of immunology (Baltimore, Md. : 1950); 182(1) pg319-28

1 Jan 2009

19109163
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Kumar, D

JNK MAPK pathway regulates constitutive transcription of CCL5 by human NK cells through SP1.

Journal of immunology (Baltimore, Md. : 1950); 182(2) pg1011-20

15 Jan 2009

19124744
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Ouaked, N

Regulation of the foxp3 gene by the Th1 cytokines: the role of IL-27-induced STAT1.

Journal of immunology (Baltimore, Md. : 1950); 182(2) pg1041-9

15 Jan 2009

19124747
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Tran, D Q

Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor function.

Journal of immunology (Baltimore, Md. : 1950); 182(5) pg2929-38

1 Mar 2009

19234188
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Fourcade, J

PD-1 is a regulator of NY-ESO-1-specific CD8+ T cell expansion in melanoma patients.

Journal of immunology (Baltimore, Md. : 1950); 182(9) pg5240-9

1 May 2009

19380770
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Lin, J T

Naive CD4 t cell proliferation is controlled by mammalian target of rapamycin regulation of GRAIL expression.

Journal of immunology (Baltimore, Md. : 1950); 182(10) pg5919-28

15 May 2009

19414743
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Rayment, R

Evidence for the specificity for platelet HPA-1a alloepitope and the presenting HLA-DR52a of diverse antigen-specific helper T cell clones from alloimmunized mothers.

Journal of immunology (Baltimore, Md. : 1950); 183(1) pg677-86

1 Jul 2009

19535639
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Hagn, M

Human B cells secrete granzyme B when recognizing viral antigens in the context of the acute phase cytokine IL-21.

Journal of immunology (Baltimore, Md. : 1950); 183(3) pg1838-45

1 Aug 2009

19592644
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Chang, B Y

JAK3 inhibition significantly attenuates psoriasiform skin inflammation in CD18 mutant PL/J mice.

Journal of immunology (Baltimore, Md. : 1950); 183(3) pg2183-92

1 Aug 2009

19596999
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Cai, Q

Helios deficiency has minimal impact on T cell development and function.

Journal of immunology (Baltimore, Md. : 1950); 183(4) pg2303-11

15 Aug 2009

19620299
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Pozo, D

Induction of alloantigen-specific human T regulatory cells by vasoactive intestinal peptide.

Journal of immunology (Baltimore, Md. : 1950); 183(7) pg4346-59

1 Oct 2009

19734220
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Tomala, J

In vivo expansion of activated naive CD8+ T cells and NK cells driven by complexes of IL-2 and anti-IL-2 monoclonal antibody as novel approach of cancer immunotherapy.

Journal of immunology (Baltimore, Md. : 1950); 183(8) pg4904-12

15 Oct 2009

19801515
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Gonzalez, V D

Expansion of functionally skewed CD56-negative NK cells in chronic hepatitis C virus infection: correlation with outcome of pegylated IFN-alpha and ribavirin treatment.

Journal of immunology (Baltimore, Md. : 1950); 183(10) pg6612-8

15 Nov 2009

19846870
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Pickard, C

The cutaneous biochemical redox barrier: a component of the innate immune defenses against sensitization by highly reactive environmental xenobiotics.

Journal of immunology (Baltimore, Md. : 1950); 183(11) pg7576-84

1 Dec 2009

19890059
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Lipscomb, M W

Ectopic T-bet expression licenses dendritic cells for IL-12-independent priming of type 1 T cells in vitro.

Journal of immunology (Baltimore, Md. : 1950); 183(11) pg7250-8

1 Dec 2009

19915058
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Godin-Ethier, J

Human activated T lymphocytes modulate IDO expression in tumors through Th1/Th2 balance.

Journal of immunology (Baltimore, Md. : 1950); 183(12) pg7752-60

15 Dec 2009

19933867
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Jarchum, I

Ins2 deficiency augments spontaneous HLA-A*0201-restricted T cell responses to insulin.

Journal of immunology (Baltimore, Md. : 1950); 184(2) pg658-65

15 Jan 2010

19966211
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Tan, A H

Pharmacologic inhibition of MEK-ERK signaling enhances Th17 differentiation.

Journal of immunology (Baltimore, Md. : 1950); 184(4) pg1849-57

15 Feb 2010

20061405
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Wooldridge, L

MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs.

Journal of immunology (Baltimore, Md. : 1950); 184(7) pg3357-66

1 Apr 2010

20190139
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Suchard, S J

An LFA-1 (alphaLbeta2) small-molecule antagonist reduces inflammation and joint destruction in murine models of arthritis.

Journal of immunology (Baltimore, Md. : 1950); 184(7) pg3917-26

1 Apr 2010

20190141
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Liu, J

A threonine-based targeting signal in the human CD1d cytoplasmic tail controls its functional expression.

Journal of immunology (Baltimore, Md. : 1950); 184(9) pg4973-81

1 May 2010

20368272
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Nesbeth, Y C

CD4+ T cells elicit host immune responses to MHC class II-negative ovarian cancer through CCL5 secretion and CD40-mediated licensing of dendritic cells.

Journal of immunology (Baltimore, Md. : 1950); 184(10) pg5654-62

15 May 2010

20400704
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Fourcade, J

Human tumor antigen-specific helper and regulatory T cells share common epitope specificity but exhibit distinct T cell repertoire.

Journal of immunology (Baltimore, Md. : 1950); 184(12) pg6709-18

15 Jun 2010

20483736
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Martin, J F

An IL-2 paradox: blocking CD25 on T cells induces IL-2-driven activation of CD56(bright) NK cells.

Journal of immunology (Baltimore, Md. : 1950); 185(2) pg1311-20

15 Jul 2010

20543101
Show Usages

Tabi, Z

Resistance of CD45RA- T cells to apoptosis and functional impairment, and activation of tumor-antigen specific T cells during radiation therapy of prostate cancer.

Journal of immunology (Baltimore, Md. : 1950); 185(2) pg1330-9

15 Jul 2010

20548027
Show Usages

Yeh, N

Tc17 cells are capable of mediating immunity to vaccinia virus by acquisition of a cytotoxic phenotype.

Journal of immunology (Baltimore, Md. : 1950); 185(4) pg2089-98

15 Aug 2010

20624947
Show Usages

Zou, T

Dendritic cells induce regulatory T cell proliferation through antigen-dependent and -independent interactions.

Journal of immunology (Baltimore, Md. : 1950); 185(5) pg2790-9

1 Sep 2010

20686126
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Ni, L

Concomitant activation and antigen uptake via human dectin-1 results in potent antigen-specific CD8+ T cell responses.

Journal of immunology (Baltimore, Md. : 1950); 185(6) pg3504-13

15 Sep 2010

20729328
Show Usages

Wooldridge, L

CD8 controls T cell cross-reactivity.

Journal of immunology (Baltimore, Md. : 1950); 185(8) pg4625-32

15 Oct 2010

20844204
Show Usages

Kastner, L

Synergistic effect of IL-6 and IL-4 in driving fate revision of natural Foxp3+ regulatory T cells.

Journal of immunology (Baltimore, Md. : 1950); 185(10) pg5778-86

15 Nov 2010

20926793
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Smith, M A

PRDM1/Blimp-1 controls effector cytokine production in human NK cells.

Journal of immunology (Baltimore, Md. : 1950); 185(10) pg6058-67

15 Nov 2010

20944005
Show Usages

Bleck, B

Diesel exhaust particle-treated human bronchial epithelial cells upregulate Jagged-1 and OX40 ligand in myeloid dendritic cells via thymic stromal lymphopoietin.

Journal of immunology (Baltimore, Md. : 1950); 185(11) pg6636-45

1 Dec 2010

20974985
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Kudela, P

Epitope hierarchy of spontaneous CD4+ T cell responses to LAGE-1.

Journal of immunology (Baltimore, Md. : 1950); 186(1) pg312-22

1 Jan 2011

21131422
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Baeke, F

The vitamin D analog, TX527, promotes a human CD4+CD25highCD127low regulatory T cell profile and induces a migratory signature specific for homing to sites of inflammation.

Journal of immunology (Baltimore, Md. : 1950); 186(1) pg132-42

1 Jan 2011

21131424
Show Usages

Okano, S

Provision of continuous maturation signaling to dendritic cells by RIG-I-stimulating cytosolic RNA synthesis of Sendai virus.

Journal of immunology (Baltimore, Md. : 1950); 186(3) pg1828-39

1 Feb 2011

21187441
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Lee, F E

Circulating human antibody-secreting cells during vaccinations and respiratory viral infections are characterized by high specificity and lack of bystander effect.

Journal of immunology (Baltimore, Md. : 1950); 186(9) pg5514-21

1 May 2011

21441455
Show Usages

Lin, J

Yersinia pestis YopE contains a dominant CD8 T cell epitope that confers protection in a mouse model of pneumonic plague.

Journal of immunology (Baltimore, Md. : 1950); 187(2) pg897-904

15 Jul 2011

21653834
Show Usages

Neunkirchner, A

Human TCR transgenic Bet v 1-specific Th1 cells suppress the effector function of Bet v 1-specific Th2 cells.

Journal of immunology (Baltimore, Md. : 1950); 187(8) pg4077-87

15 Oct 2011

21908735
Show Usages

Zhou, R

A new look at immune privilege of the eye: dual role for the vision-related molecule retinoic acid.

Journal of immunology (Baltimore, Md. : 1950); 187(8) pg4170-7

15 Oct 2011

21918194
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Gottschalk, R A

Expression of Helios in peripherally induced Foxp3+ regulatory T cells.

Journal of immunology (Baltimore, Md. : 1950); 188(3) pg976-80

1 Feb 2012

22198953
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Benoit, M E

Complement protein C1q directs macrophage polarization and limits inflammasome activity during the uptake of apoptotic cells.

Journal of immunology (Baltimore, Md. : 1950); 188(11) pg5682-93

1 Jun 2012

22523386
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Ueda, A

Fyn promotes Th17 differentiation by regulating the kinetics of RORÎ³t and Foxp3 expression.

Journal of immunology (Baltimore, Md. : 1950); 188(11) pg5247-56

1 Jun 2012

22539787
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Antal, Z

Beyond HLA-A*0201: new HLA-transgenic nonobese diabetic mouse models of type 1 diabetes identify the insulin C-peptide as a rich source of CD8+ T cell epitopes.

Journal of immunology (Baltimore, Md. : 1950); 188(11) pg5766-75

1 Jun 2012

22539795
Show Usages

Bosnjak, L

Contact-dependent interference with invariant NKT cell activation by herpes simplex virus-infected cells.

Journal of immunology (Baltimore, Md. : 1950); 188(12) pg6216-24

15 Jun 2012

22581860
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Freeley, M

L-plastin regulates polarization and migration in chemokine-stimulated human T lymphocytes.

Journal of immunology (Baltimore, Md. : 1950); 188(12) pg6357-70

15 Jun 2012

22581862
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Pham, D

Twist1 regulates Ifng expression in Th1 cells by interfering with Runx3 function.

Journal of immunology (Baltimore, Md. : 1950); 189(2) pg832-40

15 Jul 2012

22685315
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Tkach, M

Targeting Stat3 induces senescence in tumor cells and elicits prophylactic and therapeutic immune responses against breast cancer growth mediated by NK cells and CD4+ T cells.

Journal of immunology (Baltimore, Md. : 1950); 189(3) pg1162-72

1 Aug 2012

22753933
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Hervas-Stubbs, S

CD8 T cell priming in the presence of IFN-Î± renders CTLs with improved responsiveness to homeostatic cytokines and recall antigens: important traits for adoptive T cell therapy.

Journal of immunology (Baltimore, Md. : 1950); 189(7) pg3299-310

1 Oct 2012

22925929
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Overdijk, M B

Crosstalk between human IgG isotypes and murine effector cells.

Journal of immunology (Baltimore, Md. : 1950); 189(7) pg3430-8

1 Oct 2012

22956577
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Pasetto, A

TCR-redirected human T cells inhibit hepatitis C virus replication: hepatotoxic potential is linked to antigen specificity and functional avidity.

Journal of immunology (Baltimore, Md. : 1950); 189(9) pg4510-9

1 Nov 2012

23024278
Show Usages

Jeffery, L E

Availability of 25-hydroxyvitamin D(3) to APCs controls the balance between regulatory and inflammatory T cell responses.

Journal of immunology (Baltimore, Md. : 1950); 189(11) pg5155-64

1 Dec 2012

23087405
Show Usages

Soriano-Sarabia, N

Primary MHC-class II(+) cells are necessary to promote resting VÎ´2 cell expansion in response to (E)-4-hydroxy-3-methyl-but-2-enyl-pyrophosphate and isopentenyl pyrophosphate.

Journal of immunology (Baltimore, Md. : 1950); 189(11) pg5212-22

1 Dec 2012

23105138
Show Usages

Ding, B B

IL-21 and CD40L synergistically promote plasma cell differentiation through upregulation of Blimp-1 in human B cells.

Journal of immunology (Baltimore, Md. : 1950); 190(4) pg1827-36

15 Feb 2013

23325890
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Yu, J

Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer.

Journal of immunology (Baltimore, Md. : 1950); 190(7) pg3783-97

1 Apr 2013

23440412
Show Usages

Wu, S

Galectin-3 negatively regulates dendritic cell production of IL-23/IL-17-axis cytokines in infection by Histoplasma capsulatum.

Journal of immunology (Baltimore, Md. : 1950); 190(7) pg3427-37

1 Apr 2013

23455499
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Sandy, A R

T cell-specific notch inhibition blocks graft-versus-host disease by inducing a hyporesponsive program in alloreactive CD4+ and CD8+ T cells.

Journal of immunology (Baltimore, Md. : 1950); 190(11) pg5818-28

1 Jun 2013

23636056
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Edwards, J P

Regulation of the expression of GARP/latent TGF-Î²1 complexes on mouse T cells and their role in regulatory T cell and Th17 differentiation.

Journal of immunology (Baltimore, Md. : 1950); 190(11) pg5506-15

1 Jun 2013

23645881
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Pham, D

Opposing roles of STAT4 and Dnmt3a in Th1 gene regulation.

Journal of immunology (Baltimore, Md. : 1950); 191(2) pg902-11

15 Jul 2013

23772023
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Lopez, J A

Rapid and unidirectional perforin pore delivery at the cytotoxic immune synapse.

Journal of immunology (Baltimore, Md. : 1950); 191(5) pg2328-34

1 Sep 2013

23885110
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McCarthy, N E

Proinflammatory VÎ´2+ T cells populate the human intestinal mucosa and enhance IFN-Î³ production by colonic Î±Î² T cells.

Journal of immunology (Baltimore, Md. : 1950); 191(5) pg2752-63

1 Sep 2013

23904167
Show Usages

Ankri, C

Human T cells engineered to express a programmed death 1/28 costimulatory retargeting molecule display enhanced antitumor activity.

Journal of immunology (Baltimore, Md. : 1950); 191(8) pg4121-9

15 Oct 2013

24026081
Show Usages

Ponzetta, A

CX3CR1 regulates the maintenance of KLRG1+ NK cells into the bone marrow by promoting their entry into circulation.

Journal of immunology (Baltimore, Md. : 1950); 191(11) pg5684-94

1 Dec 2013

24184559
Show Usages

Arneja, A

Qualitatively different T cell phenotypic responses to IL-2 versus IL-15 are unified by identical dependences on receptor signal strength and duration.

Journal of immunology (Baltimore, Md. : 1950); 192(1) pg123-35

1 Jan 2014

24298013
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Kim, K

Calcium signaling via Orai1 is essential for induction of the nuclear orphan receptor pathway to drive Th17 differentiation.

Journal of immunology (Baltimore, Md. : 1950); 192(1) pg110-22

1 Jan 2014

24307733
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Gogoi, D

Involvement of Notch in activation and effector functions of Î³Î´ T cells.

Journal of immunology (Baltimore, Md. : 1950); 192(5) pg2054-62

1 Mar 2014

24489102
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Kim, P S

Pan-Bcl-2 inhibitor, GX15-070 (obatoclax), decreases human T regulatory lymphocytes while preserving effector T lymphocytes: a rationale for its use in combination immunotherapy.

Journal of immunology (Baltimore, Md. : 1950); 192(6) pg2622-33

15 Mar 2014

24516200
Show Usages

Lee, J

Regulator of fatty acid metabolism, acetyl coenzyme a carboxylase 1, controls T cell immunity.

Journal of immunology (Baltimore, Md. : 1950); 192(7) pg3190-9

1 Apr 2014

24567531
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Katz, G

SAP facilitates recruitment and activation of LCK at NTB-A receptors during restimulation-induced cell death.

Journal of immunology (Baltimore, Md. : 1950); 192(9) pg4202-9

1 May 2014

24688028
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Shiomi, A

GM-CSF but not IL-17 is critical for the development of severe interstitial lung disease in SKG mice.

Journal of immunology (Baltimore, Md. : 1950); 193(2) pg849-59

15 Jul 2014

24951817
Show Usages

Uhlenbrock, F

The NKG2D ligand ULBP2 is specifically regulated through an invariant chain-dependent endosomal pathway.

Journal of immunology (Baltimore, Md. : 1950); 193(4) pg1654-65

15 Aug 2014

25024379
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Glosson-Byers, N L

Th17 cells demonstrate stable cytokine production in a proallergic environment.

Journal of immunology (Baltimore, Md. : 1950); 193(6) pg2631-40

15 Sep 2014

25086171
Show Usages

Matta, B M

IL-33 is an unconventional Alarmin that stimulates IL-2 secretion by dendritic cells to selectively expand IL-33R/ST2+ regulatory T cells.

Journal of immunology (Baltimore, Md. : 1950); 193(8) pg4010-20

15 Oct 2014

25217167
Show Usages

Duquenne, C

The two human CXCR4 isoforms display different HIV receptor activities: consequences for the emergence of X4 strains.

Journal of immunology (Baltimore, Md. : 1950); 193(8) pg4188-94

15 Oct 2014

25230750
Show Usages

Arruvito, L

Identification and clinical relevance of naturally occurring human CD8+HLA-DR+ regulatory T cells.

Journal of immunology (Baltimore, Md. : 1950); 193(9) pg4469-76

1 Nov 2014

25261474
Show Usages

Pardee, A D

Tumor-derived Î±-fetoprotein impairs the differentiation and T cell stimulatory activity of human dendritic cells.

Journal of immunology (Baltimore, Md. : 1950); 193(11) pg5723-32

1 Dec 2014

25355916
Show Usages

Matsushita, K

B cell-intrinsic MyD88 signaling is essential for IgE responses in lungs exposed to pollen allergens.

Journal of immunology (Baltimore, Md. : 1950); 193(12) pg5791-800

15 Dec 2014

25367117
Show Usages

Busch, S

5-lipoxygenase is a direct target of miR-19a-3p and miR-125b-5p.

Journal of immunology (Baltimore, Md. : 1950); 194(4) pg1646-53

15 Feb 2015

25589070
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Buckley, M W

ShcA regulates late stages of T cell development and peripheral CD4+ T cell numbers.

Journal of immunology (Baltimore, Md. : 1950); 194(4) pg1665-76

15 Feb 2015

25595778
Show Usages

Boland, B S

Immunodeficiency and autoimmune enterocolopathy linked to NFAT5 haploinsufficiency.

Journal of immunology (Baltimore, Md. : 1950); 194(6) pg2551-60

15 Mar 2015

25667416
Show Usages

Apps, R

Relative expression levels of the HLA class-I proteins in normal and HIV-infected cells.

Journal of immunology (Baltimore, Md. : 1950); 194(8) pg3594-600

15 Apr 2015

25754738
Show Usages

Bornancin, F

Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation.

Journal of immunology (Baltimore, Md. : 1950); 194(8) pg3723-34

15 Apr 2015

25762782
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Kaltenmeier, C

CD4+ T cell-derived IL-21 and deprivation of CD40 signaling favor the in vivo development of granzyme B-expressing regulatory B cells in HIV patients.

Journal of immunology (Baltimore, Md. : 1950); 194(8) pg3768-77

15 Apr 2015

25780036
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Nielsen, C M

Impaired NK Cell Responses to Pertussis and H1N1 Influenza Vaccine Antigens in Human Cytomegalovirus-Infected Individuals.

Journal of immunology (Baltimore, Md. : 1950); 194(10) pg4657-67

15 May 2015

25855356
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Liu, Y

Involvement of the HCK and FGR src-family kinases in FCRL4-mediated immune regulation.

Journal of immunology (Baltimore, Md. : 1950); 194(12) pg5851-60

15 Jun 2015

25972488
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Leitner, J

CD58/CD2 Is the Primary Costimulatory Pathway in Human CD28-CD8+ T Cells.

Journal of immunology (Baltimore, Md. : 1950); 195(2) pg477-87

15 Jul 2015

26041540
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Menner, A J

Id3 Controls Cell Death of 2B4+ Virus-Specific CD8+ T Cells in Chronic Viral Infection.

Journal of immunology (Baltimore, Md. : 1950); 195(5) pg2103-14

1 Sep 2015

26232435
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Sakaguchi, S

MAZR and Runx Factors Synergistically Repress ThPOK during CD8+ T Cell Lineage Development.

Journal of immunology (Baltimore, Md. : 1950); 195(6) pg2879-87

15 Sep 2015

26254341
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Mattiola, I

Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1Î², IFN-Î², and IL-15 Pathways.

Journal of immunology (Baltimore, Md. : 1950); 195(6) pg2818-28

15 Sep 2015

26276870
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Forslund, E

Microchip-Based Single-Cell Imaging Reveals That CD56dimCD57-KIR-NKG2A+ NK Cells Have More Dynamic Migration Associated with Increased Target Cell Conjugation and Probability of Killing Compared to CD56dimCD57-KIR-NKG2A- NK Cells.

Journal of immunology (Baltimore, Md. : 1950); 195(7) pg3374-81

1 Oct 2015

26320254
Show Usages

Ma, Y

IL-4-Producing Dendritic Cells Induced during Schistosoma japonica Infection Promote Th2 Cells via IL-4-Dependent Pathway.

Journal of immunology (Baltimore, Md. : 1950); 195(8) pg3769-80

15 Oct 2015

26363056
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Hsu, P

IL-10 Potentiates Differentiation of Human Induced Regulatory T Cells via STAT3 and Foxo1.

Journal of immunology (Baltimore, Md. : 1950); 195(8) pg3665-74

15 Oct 2015

26363058
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Kim, M T

Enhancing Dendritic Cell-based Immunotherapy with IL-2/Monoclonal Antibody Complexes for Control of Established Tumors.

Journal of immunology (Baltimore, Md. : 1950); 195(9) pg4537-44

1 Nov 2015

26408669
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Iizuka, Y

UNC-45A Is a Nonmuscle Myosin IIA Chaperone Required for NK Cell Cytotoxicity via Control of Lytic Granule Secretion.

Journal of immunology (Baltimore, Md. : 1950); 195(10) pg4760-70

15 Nov 2015

26438524
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Lupar, E

Eomesodermin Expression in CD4+ T Cells Restricts Peripheral Foxp3 Induction.

Journal of immunology (Baltimore, Md. : 1950); 195(10) pg4742-52

15 Nov 2015

26453746
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Salmond, R J

Mechanistic Target of Rapamycin Complex 1/S6 Kinase 1 Signals Influence T Cell Activation Independently of Ribosomal Protein S6 Phosphorylation.

Journal of immunology (Baltimore, Md. : 1950); 195(10) pg4615-22

15 Nov 2015

26453749
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Tosh, K W

The IL-12 Response of Primary Human Dendritic Cells and Monocytes to Toxoplasma gondii Is Stimulated by Phagocytosis of Live Parasites Rather Than Host Cell Invasion.

Journal of immunology (Baltimore, Md. : 1950); 196(1) pg345-56

1 Jan 2016

26597011
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Dimeloe, S

The Immune-Metabolic Basis of Effector Memory CD4+ T Cell Function under Hypoxic Conditions.

Journal of immunology (Baltimore, Md. : 1950); 196(1) pg106-14

1 Jan 2016

26621861
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Jiang, H

LZTFL1 Upregulated by All-Trans Retinoic Acid during CD4+ T Cell Activation Enhances IL-5 Production.

Journal of immunology (Baltimore, Md. : 1950); 196(3) pg1081-90

1 Feb 2016

26700766
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Wendt, E

Glucocorticoids Suppress CCR9-Mediated Chemotaxis, Calcium Flux, and Adhesion to MAdCAM-1 in Human T Cells.

Journal of immunology (Baltimore, Md. : 1950); 196(9) pg3910-9

1 May 2016

27016601
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Nagashima, H

TNFR-Associated Factors 2 and 5 Differentially Regulate the Instructive IL-6 Receptor Signaling Required for Th17 Development.

Journal of immunology (Baltimore, Md. : 1950); 196(10) pg4082-9

15 May 2016

27076680
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Reches, A

HNRNPR Regulates the Expression of Classical and Nonclassical MHC Class I Proteins.

Journal of immunology (Baltimore, Md. : 1950); 196(12) pg4967-76

15 Jun 2016

27194785
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Verma, N K

LFA-1/ICAM-1 Ligation in Human T Cells Promotes Th1 Polarization through a GSK3Î² Signaling-Dependent Notch Pathway.

Journal of immunology (Baltimore, Md. : 1950); 197(1) pg108-18

1 Jul 2016

27206767
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Akkaya, B

A Simple, Versatile Antibody-Based Barcoding Method for Flow Cytometry.

Journal of immunology (Baltimore, Md. : 1950); 197(5) pg2027-38

1 Sep 2016

27439517
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Chheda, Z S

Chemoattractant Receptors BLT1 and CXCR3 Regulate Antitumor Immunity by Facilitating CD8+ T Cell Migration into Tumors.

Journal of immunology (Baltimore, Md. : 1950); 197(5) pg2016-26

1 Sep 2016

27465528
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Paquin-Proulx, D

Innate Invariant NKT Cell Recognition of HIV-1-Infected Dendritic Cells Is an Early Detection Mechanism Targeted by Viral Immune Evasion.

Journal of immunology (Baltimore, Md. : 1950); 197(5) pg1843-51

1 Sep 2016

27481843
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Koh, B

The ETS Family Transcription Factors Etv5 and PU.1 Function in Parallel To Promote Th9 Cell Development.

Journal of immunology (Baltimore, Md. : 1950); 197(6) pg2465-72

15 Sep 2016

27496971
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Felley, L E

Human Invariant NKT Cells Induce IL-1Î² Secretion by Peripheral Blood Monocytes via a P2X7-Independent Pathway.

Journal of immunology (Baltimore, Md. : 1950); 197(6) pg2455-64

15 Sep 2016

27534556
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Hu, X

DNA Prime-Boost Vaccine Regimen To Increase Breadth, Magnitude, and Cytotoxicity of the Cellular Immune Responses to Subdominant Gag Epitopes of Simian Immunodeficiency Virus and HIV.

Journal of immunology (Baltimore, Md. : 1950); 197(10) pg3999-4013

15 Nov 2016

27733554
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Pazdrak, K

Cytokine-Induced Glucocorticoid Resistance from Eosinophil Activation: Protein Phosphatase 5 Modulation of Glucocorticoid Receptor Phosphorylation and Signaling.

Journal of immunology (Baltimore, Md. : 1950); 197(10) pg3782-3791

15 Nov 2016

27742828
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Kuwabara, T

Acetylation Modulates IL-2 Receptor Signaling in T Cells.

Journal of immunology (Baltimore, Md. : 1950); 197(11) pg4334-4343

1 Dec 2016

27799311
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Su, K

Efficient Culture of Human Naive and Memory B Cells for Use as APCs.

Journal of immunology (Baltimore, Md. : 1950); 197(10) pg4163-4176

15 Nov 2016

27815447
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Larsen, S E

Sensitivity to Restimulation-Induced Cell Death Is Linked to Glycolytic Metabolism in Human T Cells.

Journal of immunology (Baltimore, Md. : 1950); 198(1) pg147-155

1 Jan 2017

27852741
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Hutton, A J

Human Lung Fibroblasts Present Bacterial Antigens to Autologous Lung Th Cells.

Journal of immunology (Baltimore, Md. : 1950); 198(1) pg110-118

1 Jan 2017

27895174
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Ventura, E

Cutting Edge: ERK1 Mediates the Autocrine Positive Feedback Loop of TGF-Î² and Furin in Glioma-Initiating Cells.

Journal of immunology (Baltimore, Md. : 1950); 198(12) pg4569-4574

15 Jun 2017

28484053
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Chauhan, A K

FcÎ³RIIIa Signaling Modulates Endosomal TLR Responses in Human CD4

Journal of immunology (Baltimore, Md. : 1950); 198(12) pg4596-4606

15 Jun 2017

28500073
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Lee, J

Enrichment of Human CCR6

Journal of immunology (Baltimore, Md. : 1950); 199(2) pg467-476

15 Jul 2017

28600287
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Fischer, J C

A20 Restrains Thymic Regulatory T Cell Development.

Journal of immunology (Baltimore, Md. : 1950); 199(7) pg2356-2365

1 Oct 2017

28842469
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Read, K A

Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4

Journal of immunology (Baltimore, Md. : 1950); 199(7) pg2377-2387

1 Oct 2017

28848064
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Cho, Y

The Cooperative Role of CD326

Journal of immunology (Baltimore, Md. : 1950); 199(9) pg3137-3146

1 Nov 2017

28972093
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Sabins, N C

TIM-3 Engagement Promotes Effector Memory T Cell Differentiation of Human Antigen-Specific CD8 T Cells by Activating mTORC1.

Journal of immunology (Baltimore, Md. : 1950); 199(12) pg4091-4102

15 Dec 2017

29127145
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Zhang, Y

A Cellular MicroRNA Facilitates Regulatory T Lymphocyte Development by Targeting the

Journal of immunology (Baltimore, Md. : 1950); 200(3) pg1053-1063

1 Feb 2018

29282311
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Nissen, S K

Multiple Homozygous Variants in the STING-Encoding

Journal of immunology (Baltimore, Md. : 1950); 200(10) pg3372-3382

15 May 2018

29632140
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Tan, X

Elevated Hepatic CD1d Levels Coincide with Invariant NKT Cell Defects in Chronic Hepatitis B Virus Infection.

Journal of immunology (Baltimore, Md. : 1950); 200(10) pg3530-3538

15 May 2018

29643189
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Horton, M B

Multiplexed Division Tracking Dyes for Proliferation-Based Clonal Lineage Tracing.

Journal of immunology (Baltimore, Md. : 1950); 201(3) pg1097-1103

1 Aug 2018

29914887
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Woo, J S

CRACR2A-Mediated TCR Signaling Promotes Local Effector Th1 and Th17 Responses.

Journal of immunology (Baltimore, Md. : 1950); 201(4) pg1174-1185

15 Aug 2018

29987160
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Aue, G

Activation of Th1 Immunity within the Tumor Microenvironment Is Associated with Clinical Response to Lenalidomide in Chronic Lymphocytic Leukemia.

Journal of immunology (Baltimore, Md. : 1950); 201(7) pg1967-1974

1 Oct 2018

30104242
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Zhang, T

miR-143 Regulates Memory T Cell Differentiation by Reprogramming T Cell Metabolism.

Journal of immunology (Baltimore, Md. : 1950); 201(7) pg2165-2175

1 Oct 2018

30150287
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Sharma, A

LFA-1 Ligation by High-Density ICAM-1 Is Sufficient To Activate IFN-Î³ Release by Innate T Lymphocytes.

Journal of immunology (Baltimore, Md. : 1950); 201(8) pg2452-2461

15 Oct 2018

30171164
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Imbrechts, M

Insufficient IL-10 Production as a Mechanism Underlying the Pathogenesis of Systemic Juvenile Idiopathic Arthritis.

Journal of immunology (Baltimore, Md. : 1950); 201(9) pg2654-2663

1 Nov 2018

30266771
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Wilton, K M

VASP Regulates NK Cell Lytic Granule Convergence.

Journal of immunology (Baltimore, Md. : 1950); 201(10) pg2899-2909

15 Nov 2018

30282752
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Maricic, I

Differential Activation of Hepatic Invariant NKT Cell Subsets Plays a Key Role in Progression of Nonalcoholic Steatohepatitis.

Journal of immunology (Baltimore, Md. : 1950); 201(10) pg3017-3035

15 Nov 2018

30322964
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Adam, A

Multiplexed FluoroSpot for the Analysis of Dengue Virus- and Zika Virus-Specific and Cross-Reactive Memory B Cells.

Journal of immunology (Baltimore, Md. : 1950); 201(12) pg3804-3814

15 Dec 2018

30413671
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Saverino, D

CTLA-4 (CD152) inhibits the specific lysis mediated by human cytolytic T lymphocytes in a clonally distributed fashion.

Journal of immunology (Baltimore, Md. : 1950); 162(2) pg651-8

15 Jan 1999

9916682
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Müller, J R

Selective dependence of H2-M3-restricted CD8 responses on IL-15.

Journal of immunology (Baltimore, Md. : 1950); 188(6) pg2575-82

15 Mar 2012

22312130
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Wickström, S L

A genetic defect in mice that impairs missing self recognition despite evidence for normal maturation and MHC class I-dependent education of NK cells.

Journal of immunology (Baltimore, Md. : 1950); 192(4) pg1577-86

15 Feb 2014

24442431
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Volonté, A

Cancer-initiating cells from colorectal cancer patients escape from T cell-mediated immunosurveillance in vitro through membrane-bound IL-4.

Journal of immunology (Baltimore, Md. : 1950); 192(1) pg523-32

1 Jan 2014

24277698
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Lünemann, A

A distinct subpopulation of human NK cells restricts B cell transformation by EBV.

Journal of immunology (Baltimore, Md. : 1950); 191(10) pg4989-95

15 Nov 2013

24108698
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López-Soto, A

Epithelial-mesenchymal transition induces an antitumor immune response mediated by NKG2D receptor.

Journal of immunology (Baltimore, Md. : 1950); 190(8) pg4408-19

15 Apr 2013

23509364
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Lünemann, A

A distinct subpopulation of human NK cells restricts B cell transformation by EBV.

Journal of immunology (Baltimore, Md. : 1950); 191(10) pg4989-95

15 Nov 2013

24108698
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Volonté, A

Cancer-initiating cells from colorectal cancer patients escape from T cell-mediated immunosurveillance in vitro through membrane-bound IL-4.

Journal of immunology (Baltimore, Md. : 1950); 192(1) pg523-32

1 Jan 2014

24277698
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Müller, J R

Selective dependence of H2-M3-restricted CD8 responses on IL-15.

Journal of immunology (Baltimore, Md. : 1950); 188(6) pg2575-82

15 Mar 2012

22312130
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López-Soto, A

Epithelial-mesenchymal transition induces an antitumor immune response mediated by NKG2D receptor.

Journal of immunology (Baltimore, Md. : 1950); 190(8) pg4408-19

15 Apr 2013

23509364
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Wickström, S L

A genetic defect in mice that impairs missing self recognition despite evidence for normal maturation and MHC class I-dependent education of NK cells.

Journal of immunology (Baltimore, Md. : 1950); 192(4) pg1577-86

15 Feb 2014

24442431
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Rogers, M C

CD4

Journal of immunology (Baltimore, Md. : 1950); 201(4) pg1253-1266

15 Aug 2018

29997123
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Akkaya, B

Increased Mitochondrial Biogenesis and Reactive Oxygen Species Production Accompany Prolonged CD4

Journal of immunology (Baltimore, Md. : 1950); 201(11) pg3294-3306

1 Dec 2018

30373851
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Brass, U

IFN-alpha stimulates proliferation and cytokine secretion of CD40-stimulated B cell chronic lymphocytic leukemia cells in vitro.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research; 19(4) pg335-43

0 Apr 1999

10334384
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Dimitrova, D I

Lentivirus-mediated transduction of PKR into CD34(+) hematopoietic stem cells inhibits HIV-1 replication in differentiated T cell progeny.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research; 25(6) pg345-60

0 Jun 2005

15957958
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Obad, S

Regulation of the interferon-inducible p53 target gene TRIM22 (Staf50) in human T lymphocyte activation.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research; 27(10) pg857-64

0 Oct 2007

17970695
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Metcalf, D

Stem cell factor can stimulate the formation of eosinophils by two types of murine eosinophil progenitor cells.

Stem cells (Dayton, Ohio); 20(5) pg460-9

0 2002

12351816
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Vanheusden, K

In vitro expanded cells contributing to rapid severe combined immunodeficient repopulation activity are CD34+38-33+90+45RA-.

Stem cells (Dayton, Ohio); 25(1) pg107-14

0 Jan 2007

16973833
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Okita, K

An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells.

Stem cells (Dayton, Ohio); 31(3) pg458-66

0 Mar 2013

23193063
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Giuliani, M

TLR ligands stimulation protects MSC from NK killing.

Stem cells (Dayton, Ohio); 32(1) pg290-300

0 Jan 2014

24123639
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Pan, Q

Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells.

Stem cells (Dayton, Ohio); 33(2) pg354-66

0 Feb 2015

25267273
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Amarnath, S

Bone marrow-derived mesenchymal stromal cells harness purinergenic signaling to tolerize human Th1 cells in vivo.

Stem cells (Dayton, Ohio); 33(4) pg1200-12

0 Apr 2015

25532725
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Davies, L C

Mesenchymal Stromal Cell Secretion of Programmed Death-1 Ligands Regulates T Cell Mediated Immunosuppression.

Stem cells (Dayton, Ohio); 35(3) pg766-776

0 Mar 2017

27671847
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Marguerite, M

Cellular immune responses of a Senegalese community recently exposed to Schistosoma mansoni: correlations of infection level with age and inflammatory cytokine production by soluble egg antigen-specific cells.

Tropical medicine & international health : TM & IH; 4(8) pg530-43

0 Aug 1999

10499076
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King, A G

Lineage infidelity in myeloid cells with TCR gene rearrangement: a latent developmental potential of proT cells revealed by ectopic cytokine receptor signaling.

Proceedings of the National Academy of Sciences of the United States of America; 99(7) pg4508-13

2 Apr 2002

11917122
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Li, J

Human antibodies for immunotherapy development generated via a human B cell hybridoma technology.

Proceedings of the National Academy of Sciences of the United States of America; 103(10) pg3557-62

7 Mar 2006

16505368
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Bielekova, B

Regulatory CD56(bright) natural killer cells mediate immunomodulatory effects of IL-2Ralpha-targeted therapy (daclizumab) in multiple sclerosis.

Proceedings of the National Academy of Sciences of the United States of America; 103(15) pg5941-6

11 Apr 2006

16585503
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Andreakos, E

Activation of NF-kappaB by the intracellular expression of NF-kappaB-inducing kinase acts as a powerful vaccine adjuvant.

Proceedings of the National Academy of Sciences of the United States of America; 103(39) pg14459-64

26 Sep 2006

16971487
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Sato, N

The IL-15/IL-15Ralpha on cell surfaces enables sustained IL-15 activity and contributes to the long survival of CD8 memory T cells.

Proceedings of the National Academy of Sciences of the United States of America; 104(2) pg588-93

9 Jan 2007

17202253
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Zhou, R

NKG2D recognition mediates Toll-like receptor 3 signaling-induced breakdown of epithelial homeostasis in the small intestines of mice.

Proceedings of the National Academy of Sciences of the United States of America; 104(18) pg7512-5

1 May 2007

17463084
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Wei, J

Antagonistic nature of T helper 1/2 developmental programs in opposing peripheral induction of Foxp3+ regulatory T cells.

Proceedings of the National Academy of Sciences of the United States of America; 104(46) pg18169-74

13 Nov 2007

17978190
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Rosenberger, C M

ATF3 regulates MCMV infection in mice by modulating IFN-gamma expression in natural killer cells.

Proceedings of the National Academy of Sciences of the United States of America; 105(7) pg2544-9

19 Feb 2008

18268321
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Wang, L

Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3+CD4+ regulatory T cells.

Proceedings of the National Academy of Sciences of the United States of America; 105(27) pg9331-6

8 Jul 2008

18599457
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Lewis, E C

alpha1-Antitrypsin monotherapy induces immune tolerance during islet allograft transplantation in mice.

Proceedings of the National Academy of Sciences of the United States of America; 105(42) pg16236-41

21 Oct 2008

18852465
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Parish, I A

Tissue destruction caused by cytotoxic T lymphocytes induces deletional tolerance.

Proceedings of the National Academy of Sciences of the United States of America; 106(10) pg3901-6

10 Mar 2009

19234128
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Tran, D Q

GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells.

Proceedings of the National Academy of Sciences of the United States of America; 106(32) pg13445-50

11 Aug 2009

19651619
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Leavenworth, J W

Analysis of the cellular mechanism underlying inhibition of EAE after treatment with anti-NKG2A F(ab')2.

Proceedings of the National Academy of Sciences of the United States of America; 107(6) pg2562-7

9 Feb 2010

20133787
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Adams, W C

Adenovirus type-35 vectors block human CD4+ T-cell activation via CD46 ligation.

Proceedings of the National Academy of Sciences of the United States of America; 108(18) pg7499-504

3 May 2011

21502499
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Leavenworth, J W

Mobilization of natural killer cells inhibits development of collagen-induced arthritis.

Proceedings of the National Academy of Sciences of the United States of America; 108(35) pg14584-9

30 Aug 2011

21873193
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Ostrov, D A

Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire.

Proceedings of the National Academy of Sciences of the United States of America; 109(25) pg9959-64

19 Jun 2012

22645359
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Vaeth, M

Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells.

Proceedings of the National Academy of Sciences of the United States of America; 109(40) pg16258-63

2 Oct 2012

22991461
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Benson, M J

Heterogeneous nuclear ribonucleoprotein L-like (hnRNPLL) and elongation factor, RNA polymerase II, 2 (ELL2) are regulators of mRNA processing in plasma cells.

Proceedings of the National Academy of Sciences of the United States of America; 109(40) pg16252-7

2 Oct 2012

22991471
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Reardon, C

Lymphocyte-derived ACh regulates local innate but not adaptive immunity.

Proceedings of the National Academy of Sciences of the United States of America; 110(4) pg1410-5

22 Jan 2013

23297238
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Kupz, A

Contribution of Thy1+ NK cells to protective IFN-Î³ production during Salmonella typhimurium infections.

Proceedings of the National Academy of Sciences of the United States of America; 110(6) pg2252-7

5 Feb 2013

23345426
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Donatelli, S S

TGF-Î²-inducible microRNA-183 silences tumor-associated natural killer cells.

Proceedings of the National Academy of Sciences of the United States of America; 111(11) pg4203-8

18 Mar 2014

24586048
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Dowling, M R

Stretched cell cycle model for proliferating lymphocytes.

Proceedings of the National Academy of Sciences of the United States of America; 111(17) pg6377-82

29 Apr 2014

24733943
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Wang, L

Disruption of the immune-checkpoint VISTA gene imparts a proinflammatory phenotype with predisposition to the development of autoimmunity.

Proceedings of the National Academy of Sciences of the United States of America; 111(41) pg14846-51

14 Oct 2014

25267631
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Salio, M

Essential role for autophagy during invariant NKT cell development.

Proceedings of the National Academy of Sciences of the United States of America; 111(52) pgE5678-87

30 Dec 2014

25512546
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Zorca, C E

Myosin VI regulates gene pairing and transcriptional pause release in T cells.

Proceedings of the National Academy of Sciences of the United States of America; 112(13) pgE1587-93

31 Mar 2015

25770220
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Liu, J

Immune-checkpoint proteins VISTA and PD-1 nonredundantly regulate murine T-cell responses.

Proceedings of the National Academy of Sciences of the United States of America; 112(21) pg6682-7

26 May 2015

25964334
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Sperandio, S

TOE1 is an inhibitor of HIV-1 replication with cell-penetrating capability.

Proceedings of the National Academy of Sciences of the United States of America; 112(26) pgE3392-401

30 Jun 2015

26056259
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Hammitzsch, A

CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses.

Proceedings of the National Academy of Sciences of the United States of America; 112(34) pg10768-73

25 Aug 2015

26261308
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Tilburgs, T

The HLA-G cycle provides for both NK tolerance and immunity at the maternal-fetal interface.

Proceedings of the National Academy of Sciences of the United States of America; 112(43) pg13312-7

27 Oct 2015

26460007
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Satou, Y

The retrovirus HTLV-1 inserts an ectopic CTCF-binding site into the human genome.

Proceedings of the National Academy of Sciences of the United States of America; 113(11) pg3054-9

15 Mar 2016

26929370
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Gross, C C

Impaired NK-mediated regulation of T-cell activity in multiple sclerosis is reconstituted by IL-2 receptor modulation.

Proceedings of the National Academy of Sciences of the United States of America; 113(21) pgE2973-82

24 May 2016

27162345
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Munson, D J

Identification of shared TCR sequences from T cells in human breast cancer using emulsion RT-PCR.

Proceedings of the National Academy of Sciences of the United States of America; 113(29) pg8272-7

19 Jul 2016

27307436
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Zhang, B

Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model.

Proceedings of the National Academy of Sciences of the United States of America; 113(30) pg8490-5

26 Jul 2016

27410049
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Comte, D

Engagement of SLAMF3 enhances CD4+ T-cell sensitivity to IL-2 and favors regulatory T-cell polarization in systemic lupus erythematosus.

Proceedings of the National Academy of Sciences of the United States of America; 113(33) pg9321-6

16 Aug 2016

27482100
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He, W

Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus.

Proceedings of the National Academy of Sciences of the United States of America; 113(42) pg11931-11936

18 Oct 2016

27698132
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Ryan, P L

Heterogeneous yet stable VÎ´2(+) T-cell profiles define distinct cytotoxic effector potentials in healthy human individuals.

Proceedings of the National Academy of Sciences of the United States of America; 113(50) pg14378-14383

13 Dec 2016

27911793
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Pinaud, L

Injection of T3SS effectors not resulting in invasion is the main targeting mechanism of

Proceedings of the National Academy of Sciences of the United States of America; 114(37) pg9954-9959

12 Sep 2017

28847968
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He, N

Metabolic control of regulatory T cell (Treg) survival and function by Lkb1.

Proceedings of the National Academy of Sciences of the United States of America; 114(47) pg12542-12547

21 Nov 2017

29109251
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Pan, Y

Mechanogenetics for the remote and noninvasive control of cancer immunotherapy.

Proceedings of the National Academy of Sciences of the United States of America; 115(5) pg992-997

30 Jan 2018

29343642
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Mahgoub, M

Sporadic on/off switching of HTLV-1 Tax expression is crucial to maintain the whole population of virus-induced leukemic cells.

Proceedings of the National Academy of Sciences of the United States of America; 115(6) pgE1269-E1278

6 Feb 2018

29358408
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Tanabe, K

Transdifferentiation of human adult peripheral blood T cells into neurons.

Proceedings of the National Academy of Sciences of the United States of America; 115(25) pg6470-6475

19 Jun 2018

29866841
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Bethune, M T

Isolation and characterization of NY-ESO-1-specific T cell receptors restricted on various MHC molecules.

Proceedings of the National Academy of Sciences of the United States of America; 115(45) pgE10702-E10711

6 Nov 2018

30348802
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Parks, C

Breaking tolerance with engineered class I antigen-presenting molecules.

Proceedings of the National Academy of Sciences of the United States of America; 116(8) pg3136-3145

19 Feb 2019

30728302
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Yu, F

Remodeling of ER-plasma membrane contact sites but not STIM1 phosphorylation inhibits Ca2+ influx in mitosis.

Proceedings of the National Academy of Sciences of the United States of America; 116(21) pg10392-10401

21 May 2019

31064875
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Jin, W

T cell activation and immune synapse organization respond to the microscale mechanics of structured surfaces.

Proceedings of the National Academy of Sciences of the United States of America; 116(40) pg19835-19840

1 Oct 2019

31527238
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Tanno, H

Determinants governing T cell receptor α/β-chain pairing in repertoire formation of identical twins.

Proceedings of the National Academy of Sciences of the United States of America; 117(1) pg532-540

7 Jan 2020

31879353
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Anton, O M

Trans-endocytosis of Intact IL-15Rα-IL-15 Complex From Presenting Cells Into NK Cells Favors Signaling for Proliferation

Proceedings of the National Academy of Sciences of the United States of America; 117(1) pg522-531

7 Jan 2020

31871169
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Berthon, C

In acute myeloid leukemia, B7-H1 (PD-L1) protection of blasts from cytotoxic T cells is induced by TLR ligands and interferon-gamma and can be reversed using MEK inhibitors.

Cancer immunology, immunotherapy : CII; 59(12) pg1839-49

0 Dec 2010

20814675
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Andersen, R S

Identification of a cyclin B1-derived CTL epitope eliciting spontaneous responses in both cancer patients and healthy donors.

Cancer immunology, immunotherapy : CII; 60(2) pg227-34

0 Feb 2011

20981424
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Fowler, D W

Mycobacteria activate Î³Î´ T-cell anti-tumour responses via cytokines from type 1 myeloid dendritic cells: a mechanism of action for cancer immunotherapy.

Cancer immunology, immunotherapy : CII; 61(4) pg535-47

0 Apr 2012

22002242
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Peng, S

HLA-DQB1*02-restricted HPV-16 E7 peptide-specific CD4+ T-cell immune responses correlate with regression of HPV-16-associated high-grade squamous intraepithelial lesions.

Clinical cancer research : an official journal of the American Association for Cancer Research; 13(8) pg2479-87

15 Apr 2007

17438108
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Weishaupt, C

T-cell distribution and adhesion receptor expression in metastatic melanoma.

Clinical cancer research : an official journal of the American Association for Cancer Research; 13(9) pg2549-56

1 May 2007

17473183
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Chochi, K

Helicobacter pylori augments growth of gastric cancers via the lipopolysaccharide-toll-like receptor 4 pathway whereas its lipopolysaccharide attenuates antitumor activities of human mononuclear cells.

Clinical cancer research : an official journal of the American Association for Cancer Research; 14(10) pg2909-17

15 May 2008

18483357
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Bergmann, C

T regulatory type 1 cells in squamous cell carcinoma of the head and neck: mechanisms of suppression and expansion in advanced disease.

Clinical cancer research : an official journal of the American Association for Cancer Research; 14(12) pg3706-15

15 Jun 2008

18559587
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Su, Z

Differentiation of human embryonic stem cells into immunostimulatory dendritic cells under feeder-free culture conditions.

Clinical cancer research : an official journal of the American Association for Cancer Research; 14(19) pg6207-17

1 Oct 2008

18829500
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Trimble, C L

A phase I trial of a human papillomavirus DNA vaccine for HPV16+ cervical intraepithelial neoplasia 2/3.

Clinical cancer research : an official journal of the American Association for Cancer Research; 15(1) pg361-7

1 Jan 2009

19118066
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Ueda, R

Systemic inhibition of transforming growth factor-beta in glioma-bearing mice improves the therapeutic efficacy of glioma-associated antigen peptide vaccines.

Clinical cancer research : an official journal of the American Association for Cancer Research; 15(21) pg6551-9

1 Nov 2009

19861464
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Wang, L

Immunotherapy for human renal cell carcinoma by adoptive transfer of autologous transforming growth factor beta-insensitive CD8+ T cells.

Clinical cancer research : an official journal of the American Association for Cancer Research; 16(1) pg164-73

1 Jan 2010

20028741
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Mann, K K

A retinoid/butyric acid prodrug overcomes retinoic acid resistance in leukemias by induction of apoptosis.

Molecular cancer research : MCR; 1(12) pg903-12

0 Oct 2003

14573791
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Tsukada, H

Evaluation of D-isomers of O-11C-methyl tyrosine and O-18F-fluoromethyl tyrosine as tumor-imaging agents in tumor-bearing mice: comparison with L- and D-11C-methionine.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine; 47(4) pg679-88

0 Apr 2006

16595503
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Scobie, L

A novel model of SCID-X1 reconstitution reveals predisposition to retrovirus-induced lymphoma but no evidence of gammaC gene oncogenicity.

Molecular therapy : the journal of the American Society of Gene Therapy; 17(6) pg1031-8

0 Jun 2009

19337236
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Li, Y

Aberrant CD200/CD200R1 expression and function in systemic lupus erythematosus contributes to abnormal T-cell responsiveness and dendritic cell activity.

Arthritis research & therapy; 14(3) pgR123

23 May 2012

22621248
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Husak, Z

CD99 ligation upregulates HSP70 on acute lymphoblastic leukemia cells and concomitantly increases NK cytotoxicity.

Cell death & disease; 3 pge425

15 Nov 2012

23152061
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Liu, X

MiRNA-296-3p-ICAM-1 axis promotes metastasis of prostate cancer by possible enhancing survival of natural killer cell-resistant circulating tumour cells.

Cell death & disease; 4 pge928

21 Nov 2013

24263102
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Wang, Y

DNA-PK-mediated phosphorylation of EZH2 regulates the DNA damage-induced apoptosis to maintain T-cell genomic integrity.

Cell death & disease; 7(7) pge2316

28 Jul 2016

27468692
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Xing, Y

TLR and NLRP3 inflammasome-dependent innate immune responses to tumor-derived autophagosomes (DRibbles).

Cell death & disease; 7(8) pge2322

4 Aug 2016

27490927
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Mao, F

Increased tumor-infiltrating CD45RA

Cell death & disease; 8(8) pge3002

17 Aug 2017

28817117
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Wei, S

Dysfunctional immunoregulation in human liver allograft rejection associated with compromised galectin-1/CD7 pathway function.

Cell death & disease; 9(3) pg293

20 Feb 2018

29463785
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Xue, Y

Indoleamine 2,3-dioxygenase expression regulates the survival and proliferation of Fusobacterium nucleatum in THP-1-derived macrophages.

Cell death & disease; 9(3) pg355

2 Mar 2018

29500439
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Xie, X

A dual-function epidermal growth factor receptor pathway substrate 8 (Eps8)-derived peptide exhibits a potent cytotoxic T lymphocyte-activating effect and a specific inhibitory activity.

Cell death & disease; 9(3) pg379

7 Mar 2018

29515106
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Hu, Q

Resting T cells are hypersensitive to DNA damage due to defective DNA repair pathway.

Cell death & disease; 9(6) pg662

31 May 2018

29855463
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Mao, F

CD45

Cell death & disease; 9(7) pg763

9 Jul 2018

29988030
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Khamaikawin, W

Combined Antiviral Therapy Using Designed Molecular Scaffolds Targeting Two Distinct Viral Functions, HIV-1 Genome Integration and Capsid Assembly.

Molecular therapy. Nucleic acids; 4 pge249

25 Aug 2015

26305555
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Grier, A E

pEVL: A Linear Plasmid for Generating mRNA IVT Templates With Extended Encoded Poly(A) Sequences.

Molecular therapy. Nucleic acids; 5 pge306

19 Apr 2016

27093168
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Romano Ibarra, G S

Efficient Modification of the CCR5 Locus in Primary Human T Cells With megaTAL Nuclease Establishes HIV-1 Resistance.

Molecular therapy. Nucleic acids; 5(8) pge352

23 Aug 2016

27741222
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Min, J

Inflammation induces two types of inflammatory dendritic cells in inflamed lymph nodes.

Experimental & molecular medicine; 50(3) pge458

16 Mar 2018

29546878
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Suzuki, T

Induction of antitumor immunity against mouse carcinoma by baculovirus-infected dendritic cells.

Cellular & molecular immunology; 7(6) pg440-6

0 Nov 2010

20871626
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Wang, Y

Growth of human colorectal cancer SW1116 cells is inhibited by cytokine-induced killer cells.

Clinical & developmental immunology; 2011 pg621414

0 2011

21455282
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Yang, D

Evaluation of Epstein-Barr virus latent membrane protein 2 specific T-cell receptors driven by T-cell specific promoters using lentiviral vector.

Clinical & developmental immunology; 2011 pg716926

0 2011

21969838
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Schilling, B

IRX-2, a novel biologic, favors the expansion of T effector over T regulatory cells in a human tumor microenvironment model.

Journal of molecular medicine (Berlin, Germany); 90(2) pg139-47

0 Feb 2012

21915712
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Lai, F

Cell docking, movement and cell-cell interactions of heterogeneous cell suspensions in a cell manipulation microdevice.

Sensors (Basel, Switzerland); 11(10) pg9613-27

0 2011

22163716
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Vamos, C A

Knowledge, Behavioral, and Sociocultural Factors Related to Human Papillomavirus Infection and Cervical Cancer Screening Among Inner-City Women in Panama.

Journal of community health; 40(6) pg1047-56

0 Dec 2015

25947012
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