Recombinant Human IL-8 (CXCL8) (72 a.a.) 0 ReviewsSubmit a Review Product Details Catalogue Number: 200-08M Description: IL-8 is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is secreted by monocytes and endothelial cells. IL-8 chemoattracts and activates neutrophils. Recombinant Human IL-8 (monocyte-derived) is an 8.4 kDa protein containing 72 amino acid residues. Source: E.coli Synonyms: CXCL8, monocyte-derived neutrophil chemotactic factor (MDNCF), neutrophil activating factor (NAF), NAP-1 AA Sequence: SAKELRCQCI KTYSKPFHPK FIKELRVIES GPHCANTEII VKLSDGRELC LDPKENWVQR VVEKFLKRAE NS Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 8.4 kDa Accession Number: P10145 Gene ID: 3576 crossreactivity: Bacteria, Human, Human + Rat, Monkey, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 Angiogenesis/Cardiovascular Apoptosis Chemotaxis Immune System Inflammation Neurobiology Wound Healing Allergy Transplantation product.subtitle.recentcitations First Author Dietachmayr, M Title Antagonistic activities of CDC14B and CDK1 on USP9X regulate WT1-dependent mitotic transcription and survival. Citation Nature Communications; 11(1) pg1268 PubMed Id 32152317 First Author Frommhold, D Title Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation. Citation The Journal of Experimental Medicine; 205(6) pg1435-46 PubMed Id 18519646 First Author Schröder, R Title The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation. Citation The Journal of Biological Chemistry; 284(2) pg1324-36 PubMed Id 19010788
