Recombinant Human MCP-1 (CCL2) 0 AvisSubmit a Review Détails du Produit Catalog Number: 300-04 Description: The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Human MCP-1 is an 8.6 kDa protein containing 76 amino acid residues, including the four highly conserved cysteine residues present in the CC chemokines. Source: E.coli Synonyms: Monocyte Chemotactic Protein-1, CCL2, MCAF, JE (murine) AA Sequence: QPDAINAPVT CCYNFTNRKI SVQRLASYRR ITSSKCPKEA VIFKTIVAKE ICADPKQKWV QDSMDHLDKQ TQTPKT Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 8.6 kDa Accession Number: P13500 Gene ID: 6347 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Chicken, Hamster, Human, Human + Mouse, Human + Parasite, Human + Rat, Monkey, Mouse, Pig, Rat References PubMed SDS Recherche de CoA Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 Angiogenesis/Cardiovascular Cancer Chemotaxis Immune System Inflammation Neurobiology Wound Healing Allergy product.subtitle.recentcitations Premier Auteur Bluhmki, T Titre Functional human iPSC-derived alveolar-like cells cultured in a miniaturized 96‑Transwell air-liquid interface model. Citation Scientific Reports; 11(1) pg17028 Id PubMed 34426605 Premier Auteur Fang, W B Titre Expression of CCL2/CCR2 signaling proteins in breast carcinoma cells is associated with invasive progression Citation Scientific Reports; 11(1) pg8708 Id PubMed 33888841 Premier Auteur Ocaña-Guzmán, R Titre Leukocytes from Patients with Drug-Sensitive and Multidrug-Resistant Tuberculosis Exhibit Distinctive Profiles of Chemokine Receptor Expression and Migration Capacity. Citation Journal Of Immunology Research; 2021 pg6654220 Id PubMed 33977111
