Chémokines

Recombinant Human MCP-1 (CCL2)

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Product Details

Catalogue Number: 300-04
Description:
Recombinant Human MCP-1 (CCL2)

The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Human MCP-1 is an 8.6 kDa protein containing 76 amino acid residues, including the four highly conserved cysteine residues present in the CC chemokines.

Source: E.coli

Synonyms: Monocyte Chemotactic Protein-1, CCL2, MCAF, JE (murine)

AA Sequence: QPDAINAPVT CCYNFTNRKI SVQRLASYRR ITSSKCPKEA VIFKTIVAKE ICADPKQKWV QDSMDHLDKQ TQTPKT

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml.

Calculated Molecular Weight: 8.6 kDa

Accession Number: P13500

Gene ID: 6347

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Bluhmki, T
Title
Functional human iPSC-derived alveolar-like cells cultured in a miniaturized 96‑Transwell air-liquid interface model.
Citation
Scientific Reports; 11(1) pg17028
PubMed Id
First Author
Fang, W B
Title
Expression of CCL2/CCR2 signaling proteins in breast carcinoma cells is associated with invasive progression
Citation
Scientific Reports; 11(1) pg8708
PubMed Id
First Author
Ocaña-Guzmán, R
Title
Leukocytes from Patients with Drug-Sensitive and Multidrug-Resistant Tuberculosis Exhibit Distinctive Profiles of Chemokine Receptor Expression and Migration Capacity.
Citation
Journal Of Immunology Research; 2021 pg6654220
PubMed Id