Chémokines

Recombinant Human MIP-3 (CCL23)

Product Details

Catalogue Number: 300-29
Description:

MIP-3 is a CC chemokine that signals through the CCR1 receptor. MIP-3 chemoattracts monocytes, resting T-lymphocytes, and neutrophils, but does not chemoattract activated lymphocytes. Additionally, MIP-3 has been shown to inhibit colony formation of bone marrow myeloid immature progenitors. Recombinant Human MIP-3 is an 11.3 kDa protein containing 99 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Source: E.coli

Synonyms: Macrophage Inflammatory Protein-3, CCL23, MPIF-1, Ck-β8

AA Sequence: RVTKDAETEF MMSKLPLENP VLLDRFHATS ADCCISYTPR SIPCSLLESY FETNSECSKP GVIFLTKKGR RFCANPSDKQ VQVCMRMLKL DTRIKTRKN

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human T cell population using a concentration of 10-50 ng/ml.

Calculated Molecular Weight: 11.3 kDa

Accession Number: P55773

Gene ID: 6368

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Krishnan, V
Title
Omental macrophages secrete chemokine ligands that promote ovarian cancer colonization of the omentum via CCR1
Citation
Communications Biology; 3(1) pg524
PubMed Id
First Author
Lee, A W
Title
A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.
Citation
The Journal of Biological Chemistry; 294(29) pg11199-11212
PubMed Id
First Author
Binti Mohd Amir, N A
Title
Evidence for the Existence of a CXCL17 Receptor Distinct from GPR35.
Citation
Journal of immunology (Baltimore, Md. : 1950); 201(2) pg714-724
PubMed Id