Chémokines

Recombinant Human TARC (CCL17)

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Product Details

Catalogue Number: 300-30
Description:

TARC, a CC chemokine, is predominantly produced by dendritic cells in the thymus, and signals through the CCR4 receptor. TARC is chemotactic towards T cells. Recombinant Human TARC is an 8.0 kDa protein containing 71 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

Source: E.coli

Synonyms: Thymus and Activation Regulated Chemokine, CCL17, ABCD-2

AA Sequence: ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human T cells using a concentration range of 1.0-10.0 ng/ml.

Calculated Molecular Weight: 8 kDa

Accession Number: Q92583

Gene ID: 6361

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Zhang, Y
Title
A new antagonist for CCR4 attenuates allergic lung inflammation in a mouse model of asthma.
Citation
Scientific Reports; 7(1) pg15038
PubMed Id
First Author
Wright, D E
Title
Hematopoietic stem cells are uniquely selective in their migratory response to chemokines.
Citation
The Journal of Experimental Medicine; 195(9) pg1145-54
PubMed Id
First Author
Bégué, E
Title
Inducible expression and pathophysiologic functions of T-plastin in cutaneous T-cell lymphoma.
Citation
Blood; 120(1) pg143-54
PubMed Id