Recombinant Human TGF-α 1 ReviewsSubmit a Review Product Details Catalogue Number: 100-16A Description: TGF-α is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces anchorage-independence transformation in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant Human TGF-α is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds. Source: E.coli Synonyms: Transforming Growth Factor-α, Sacroma growth factor, TGF-type I, ETGF AA Sequence: VVSHFNDCPD SHTQFCFHGT CRFLVQEDKP ACVCHSGYVG ARCEHADLLA Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BALB/c 3T3 cells is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg. Calculated Molecular Weight: 5.5 kDa Accession Number: P01135 Gene ID: 7039 crossreactivity: Chicken, Horse, Human, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Cancer Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing product.subtitle.recentcitations First Author Zhang, X Title Epidermal growth factor receptor (EGFR) signaling regulates epiphyseal cartilage development through β-catenin-dependent and -independent pathways. Citation The Journal of Biological Chemistry; 288(45) pg32229-40 PubMed Id 24047892 First Author Sanghvi, V Title The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase. Citation Cell; 178(4) pg807-819.e21 PubMed Id 31398338 First Author Pasupuleti, M Title Antimicrobial activity of human prion protein is mediated by its N-terminal region. Citation PLoS ONE; 4(10) pge7358 PubMed Id 19809501 product.subtitle.productreviews Existing reviews High quality and better price This product worked well for my project. The price is reasonable and lower than most of vendors. From: Jin | Date: 26/08/2020 × High quality and better price This product worked well for my project. The price is reasonable and lower than most of vendors. From: Jin | Date: 26/08/2020 Close
