Chémokines

Recombinant Murine BCA-1/BLC (CXCL13)

Product Details

Catalogue Number: 250-24
Description:

BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor, CXCR5. BCA-1/BLC is a potent chemoattractant for B lymphocytes, and induces weak chemotactic response in T cells and macrophages. It manifests no activity on neutrophils and monocytes. Recombinant Murine BLC is a 9.8 kDa protein containing 88 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines.

Source: E.coli

Synonyms: B cell Attracting Chemokine-1, CXCL13, BLC (mouse), BLR1 Ligand

AA Sequence: ILEAHYTNLK CRCSGVISTV VGLNIIDRIQ VTPPGNGCPK TEVVIWTKMK KVICVNPRAK WLQRLLRHVQ SKSLSSTPQA PVSKRRAA

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human B cells.

Calculated Molecular Weight: 9.8 kDa

Accession Number: O55038

Gene ID: 55985

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Ma, L
Title
ZNF382 controls mouse neuropathic pain via silencer-based epigenetic inhibition of Cxcl13 in DRG neurons.
Citation
The Journal of Experimental Medicine; 218(12)
PubMed Id
First Author
Cruz-Zárate, D
Title
Myo1g is required for efficient adhesion and migration of activated B lymphocytes to inguinal lymph nodes
Citation
Scientific Reports; 11(1) pg7197
PubMed Id
First Author
Shi, J
Title
PD-1 Controls Follicular T Helper Cell Positioning and Function.
Citation
Immunity; 49(2) pg264-274.e4
PubMed Id