Recombinant Murine LIX (CXCL6) (92 a.a.) 0 ReviewsSubmit a Review Product Details Catalogue Number: 250-17 Description: CXCL6, also known as LIX in mice, is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. LIX is a chemoattractant for neutrophils. The two naturally occurring variants of LIX, LIX 1-78 (GCP-2) and LIX 9-78 (GCP-2), contain 78 and 70 amino acid residues, respectively. LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the ‘ELR’ motif common to CXC chemokines that binds to the CXCR1 and CXCR2 receptors. Recombinant Murine LIX is a 9.8 kDa protein containing 92 amino acid residues. Source: E.coli Synonyms: CXCL6, GCP-2 (human), Granulocyte Chemotactic Protein-2 AA Sequence: APSSVIAATE LRCVCLTVTP KINPKLIANL EVIPAGPQCP TVEVIAKLKN QKEVCLDPEA PVIKKIIQKI LGSDKKKAKR NALAVERTAS VQ Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Not available. Calculated Molecular Weight: 9.8 kDa Accession Number: P50228 Gene ID: 20311 crossreactivity: Human, Mouse References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Bone, Skeletal, Cartilage Chemotaxis Immune System Inflammation Wound Healing product.subtitle.recentcitations First Author Singh, K Title Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities. Citation Scientific Reports; 7(1) pg4267 PubMed Id 28655871 First Author Mei, J Title CXCL5 regulates chemokine scavenging and pulmonary host defense to bacterial infection. Citation Immunity; 33(1) pg106-17 PubMed Id 20643340 First Author Yagawa, Y Title Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy. Citation Scientific Reports; 7(1) pg15996 PubMed Id 29167448
