Recombinant Murine LIX (CXCL6) (92 a.a.)

Détails du Produit

Catalog Number: 250-17

Description:

CXCL6, also known as LIX in mice, is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. LIX is a chemoattractant for neutrophils. The two naturally occurring variants of LIX, LIX 1-78 (GCP-2) and LIX 9-78 (GCP-2), contain 78 and 70 amino acid residues, respectively. LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the ‘ELR’ motif common to CXC chemokines that binds to the CXCR1 and CXCR2 receptors. Recombinant Murine LIX is a 9.8 kDa protein containing 92 amino acid residues.

Source: E.coli

Synonyms: CXCL6, GCP-2 (human), Granulocyte Chemotactic Protein-2

AA Sequence: APSSVIAATE LRCVCLTVTP KINPKLIANL EVIPAGPQCP TVEVIAKLKN QKEVCLDPEA PVIKKIIQKI LGSDKKKAKR NALAVERTAS VQ

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human neutrophils using a concentration range of 10-100 ng/ml.

Cross Reactivity:

Human , Mouse

Research Interest

Immune System

Inflammation

Wound Healing

Angiogenesis/Cardiovascular

Bone, Skeletal, Cartilage

Country Of Origin: USA

Not for human use.

Products Cited

Cross-Reactivity

Applications

250-15, 250-11, 250-17,

Mouse

in vitro

Products Cited

Cross-Reactivity

Applications

250-17, 315-03, 250-20A,

Mouse

in vitro

Products Cited

Cross-Reactivity

Applications

200-08M, 250-17, 300-17,

Human

in vitro

Products Cited

Cross-Reactivity

Applications

250-11, 250-17,

Mouse

in vitro

Products Cited

Cross-Reactivity

Applications

250-01, 250-04, 250-12, 250-14, 250-16, 250-17, 250-22, 250-24, 250-26, 250-27B, 250-30, 300-04, 300-29, 300-37, 300-45, 250-06, 250-08, 250-13, 250-18, 250-20A, 250-20B, 250-23, 250-27, 250-29, 250-32, 300-14, 300-16, 300-20, 300-30, 300-31, 300-34, 300-38, 300-39, 300-40, 300-41, 300-43, 300-44, 300-48,

Human

in vitro

Products Cited

Cross-Reactivity

Applications

250-15, 250-36, 250-11, 250-17,

Mouse

in vitro

Products Cited

Cross-Reactivity

Applications

250-01, 250-04, 250-06, 250-07, 250-10, 250-11, 250-12, 250-13, 250-15, 250-16, 250-17, 250-18, 250-20A, 250-20B, 250-22, 250-23, 250-24, 250-26, 250-27, 250-27B, 250-28, 250-29, 250-30, 250-32, 250-36, 250-37, 250-39,

Mouse

Binding Assay

300-34, 300-11, 300-15, 300-29B, 300-46, 300-48, 300-54, 300-08, 300-28A, 300-43, 300-45, 300-31, 300-36A, 300-14, 300-39, 300-55, 300-16, 300-28B, 300-22, 300-44, 300-33, 300-26, 300-38, 300-57, 300-24, 300-40, 300-41, 300-30, 300-12, 300-50, 300-47, 300-29A, 300-35, 300-17, 300-09, 300-56, 300-04, 300-21,

Human

in vitro

Products Cited

Cross-Reactivity

Applications

250-10, 250-09, 250-32, 250-07, 250-06, 250-08, 250-14, 250-12, 250-01, 250-04, 250-27B, 250-27, 250-13, 250-23, 250-22, 250-26, 250-30, 250-11, 250-15, 250-39, 250-17, 250-18, 250-16, 250-29, 250-20B, 250-37, 250-28,

Mouse

in vitro

300-44, 300-34, 300-41, 200-08,

Human

in vitro

Products Cited

Cross-Reactivity

Applications

300-04, 250-10, 100-42,

in vitro

250-10,

Mouse

in vitro

300-04, 100-42,

Mass Spectrometry

250-10, 250-17,

Mouse

Chemotaxis Assay

Chémokines