Chémokines

Recombinant Murine MEC (CCL28)

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Product Details

Catalogue Number: 250-30
Description:

MEC is a secreted CC chemokine expressed primarily by epithelial cells of the bronchioles, salivary gland, mammary gland and colon. MEC signals through the CCR10 receptor, and chemoattracts resting CD4, CD8 T-cells and eosinophils. MEC contains six cysteines, including the four highly conserved cysteine residues present in CC chemokines. Recombinant Murine MEC is a 12.6 kDa protein containing 111 amino acid residues.

Source: E.coli

Synonyms: Mucosae-associated Epithelial Chemokine, CCL28, CCK-1

AA Sequence: SEAILPMASS CCTEVSHHVS GRLLERVSSC SIQRADGDCD LAAVILHVKR RRICISPHNR TLKQWMRASE VKKNGRENVC SGKKQPSRKD RKGHTTRKHR TRGTHRHEAS R

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract murine lymphocytes using a concentration range of 1.0-10.0 ng/ml.

Calculated Molecular Weight: 12.6 kDa

Accession Number: Q9JIL2

Gene ID: 56838

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Singh, K
Title
Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.
Citation
Scientific Reports; 7(1) pg4267
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First Author
Yagawa, Y
Title
Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy.
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Scientific Reports; 7(1) pg15996
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First Author
Weller, C L
Title
Leukotriene B4, an activation product of mast cells, is a chemoattractant for their progenitors.
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The Journal of Experimental Medicine; 201(12) pg1961-71
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