Recombinant Murine MIP-2 (CXCL2) 0 ReviewsSubmit a Review Product Details Catalogue Number: 250-15 Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Murine MIP-2 is a 7.8 kDa protein consisting of 73 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2. Source: E.coli Synonyms: Macrophage Inflammatory Protein-2α, MIP-2α, Growth Regulated Protein/Melanoma Growth Stimulatory Activity (MGSAβ), CXCL2, GRO2 AA Sequence: AVVASELRCQ CLKTLPRVDF KNIQSLSVTP PGPHCAQTEV IATLKGGQKV CLDPEAPLVQ KIIQKILNKG KAN Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract total human neutrophils using a concentration range of 1.0-10.0 ng/ml. Calculated Molecular Weight: 7.8 kDa Accession Number: P10889 Gene ID: 20310 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Mouse, Mouse + Bacteria, Mouse + Rat, Pig References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Chemotaxis Immune System Inflammation Neurobiology Wound Healing product.subtitle.recentcitations First Author Yoon, Y Title Activation of the adipocyte CREB/CRTC pathway in obesity. Citation Communications Biology; 4(1) pg1214 PubMed Id 34686752 First Author Chen, X Title Pinaverium Bromide Attenuates Lipopolysaccharide-Induced Excessive Systemic Inflammation via Inhibiting Neutrophil Priming. Citation Journal of immunology (Baltimore, Md. : 1950); 206(8) pg1858-1865 PubMed Id 33771933 First Author Fonseca, K L Title Deficiency in the glycosyltransferase Gcnt1 increases susceptibility to tuberculosis through a mechanism involving neutrophils Citation Mucosal Immunology; 13(5) pg836-848 PubMed Id 32203062
