Recombinant Murine MIP-2 (CXCL2) 0 ReviewsSubmit a Review Product Details Catalogue Number: 250-15 Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Murine MIP-2 is a 7.8 kDa protein consisting of 73 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2. Source: E.coli Synonyms: Macrophage Inflammatory Protein-2α, MIP-2α, Growth Regulated Protein/Melanoma Growth Stimulatory Activity (MGSAβ), CXCL2, GRO2 AA Sequence: AVVASELRCQ CLKTLPRVDF KNIQSLSVTP PGPHCAQTEV IATLKGGQKV CLDPEAPLVQ KIIQKILNKG KAN Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract total human neutrophils using a concentration range of 1.0-10.0 ng/ml. Calculated Molecular Weight: 7.8 kDa Accession Number: P10889 Gene ID: 20310 crossreactivity: Human, Mouse, Mouse + Bacteria, Mouse + Rat, Pig References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Chemotaxis Immune System Inflammation Neurobiology Wound Healing product.subtitle.recentcitations First Author Liou, G Title Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs. Citation The Journal of Cell Biology; 202(3) pg563-77 PubMed Id 23918941 First Author Kim, S Y Title Bone marrow-derived cells require a functional glucose 6-phosphate transporter for normal myeloid functions. Citation The Journal of Biological Chemistry; 281(39) pg28794-801 PubMed Id 16891306 First Author Gilbert, L A Title DNA damage-mediated induction of a chemoresistant niche. Citation Cell; 143(3) pg355-66 PubMed Id 21029859
