Recombinant Rat FGF-10 0 ReviewsSubmit a Review Product Details Catalogue Number: 400-42 Description: FGF‐10 is a heparin‐binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF‐10 is most related to KGF/FGF‐7, and is expressed during the development and, preferentially, in adult lungs. It signals through FGFR 2b. Recombinant Rat FGF‐10 is a 20.2 kDa protein consisting of 180 amino acid residues. Source: E.coli Synonyms: Fibroblast Growth Factor‐10, FGFA, Keratinocyte Growth Factor‐2 AA Sequence: MQALGQDMVS PEATNSSSSS SSSSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR GQKTRRKNTS AHFLPMVVHS Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Assay #1: Determined by dose-dependent ability to reduce tetrazolium salt, WST-8, by dehydrogenase activities of BaF3 cells expressing FGF receptors using Cell Counting Kit-8 (CCK-8). Assay #2: Determined by a cell proliferation assay using 4MBr-5 cells. The expected ED50 for this effect is 1-5 ng/ml. Calculated Molecular Weight: 20.2 kDa Accession Number: P70492 Gene ID: 25443 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Organoids Angiogenesis/Cardiovascular Bone, Skeletal, Cartilage Cancer FGF Superfamily Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing
