Recombinant Rat GM-CSF 0 ReviewsSubmit a Review Product Details Catalogue Number: 400-23 Description: GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages, and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant Rat GM-CSF is a 14.5 kDa globular protein consisting of 128 amino acid residues. Source: E.coli Synonyms: Granulocyte-Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, Pluripoietin-α AA Sequence: MAPTRSPNPV TRPWKHVDAI KEALSLLNDM RALENEKNED VDIISNEFSI QRPTCVQTRL KLYKQGLRGN LTKLNGALTM IASHYQTNCP PTPETDCEIE VTTFEDFIKN LKGFLFDIPF DCWKPVQK Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of Murine FDC-P1 cells is ≤ 0.01 ng/ml, corresponding to a specific activity of ≥ 1 x 108 units/mg. Calculated Molecular Weight: 14.5 kDa Accession Number: P48750 Gene ID: 116630 crossreactivity: Human, Mouse, Rabbit, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 Cancer Cell Culture Immune System Inflammation Stem Cells & Differentiation Wound Healing product.subtitle.recentcitations First Author Pickard, M R Title Robust uptake of magnetic nanoparticles (MNPs) by central nervous system (CNS) microglia: implications for particle uptake in mixed neural cell populations. Citation International Journal of Molecular Sciences; 11(3) pg967-81 PubMed Id 20479995 First Author Togni, M Title The adapter protein ADAP is required for selected dendritic cell functions. Citation Cell communication and signaling : CCS; 10(1) pg14 PubMed Id 22672517 First Author Li, D Title Nano-sized Al Citation Cell death & disease; 9(8) pg840 PubMed Id 30082761
