Recombinant Rat IL-5 0 ReviewsSubmit a Review Product Details Catalogue Number: 400-05 Description: IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Recombinant Rat IL-5 is a 26.0 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains. Source: E.coli Synonyms: EDF, BCDFII, TRF AA Sequence: MEIPMSTVVK ETLIQLSTHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEILFQNL SLIKKYIDGQ KEKCGEERRK TRHFLDYLQE FLGVMSTEWA MEV Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg. Calculated Molecular Weight: 26 kDa Accession Number: Q08125 Gene ID: 24497 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Note: 200μg is the largest vial size for this product. Larger sizes supplied as multiple 100-200μg vials. crossreactivity: Human PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 Immune System Inflammation Wound Healing Allergy
