Ruxolitinib Détails du Produit Catalog Number: 9414958 Description: Ruxolitinib is a potent Janus-associated Kinase (JAK1 IC50 2.7nM, JAK2 IC50 4.5nM) inhibitor. JAK1 and JAK2 transduce cytokine-mediated signals and are involved in interferon-gamma signaling. Ruxolitinib is reported to block IL-6 signaling and inhibits the proliferation of erythroid progenitors. Synonyms: INCB018424, Jakavi, Jakafi, INCB-018424 Application: Formulation: Crystalline solid Chemical Name: (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile Molecular Formula: C17H18N6 Molecular Weight: 306.4 CAS Number: 941678-49-5 Purity: ≥98% Note: Product supplied by Biogems Research Interest Cancer Product Line Country Of Origin: USA Not for human use.
