U0126 Product Details Catalogue Number: 1095821 Description: U0126 is a highly selective inhibitor of MEK1 (IC50 of 72nM) and MEK2 (IC50 of 58nM) that antagonizes AP-1 transcriptional activity. U0216 helps maintain human pluripotent stem cells in the undifferentiated state. It is also reported to sensitize cells to anoikis, as upon treatment with U0126 cells deprived of anchorage enter apoptosis. Synonyms: U-0126, UO-126 Application: Formulation: Crystalline solid Chemical Name: (2Z,3Z)-2,3-bis[amino-(2-aminophenyl)sulfanylmethylidene]butanedinitrile Molecular Formula: C18H16N6S2 Molecular Weight: 380.5 CAS Number: 109511-58-2 Purity: ≥98% Note: Product supplied by Biogems Country Of Origin: USA Not for human use. CoA Search Product Line Research Interest Stem Cells & Differentiation
