Monoclonal Antibodies

Biogems

Anti-Mouse CD45 Purified (Clone#: 30-F11)

Product Details

Catalog Number: 07512-20
Description:
The 30-F11 monoclonal antibody specifically reacts with all isoforms of CD45 and also with the alloantigens CD45.1 and CD45.2 (LCA). CD45 is a transmembrane glycoprotein, expressed by all the hematopoietic cells, except for platelets and mature erythrocytes, which distinguishes the leukocytes from the non-hematopoietic cells. The CD45 molecule is a member of the Protein Tyrosine Phosphatase (PTP) family, because its intracellular region contains two PTP domains. The extracellular region’s variability is caused by different levels of glycosylation, and the splicing of the 4, 5, and 6 exons.The isoforms found in the mouse strains depend on the activation state, maturation stage and cell type, and are very important in B and T lymphocytes antigen receptor signal transduction.

Source: Isotype: Rat IgG2b, kappa; Clone#: 30-F11

Note:

Product supplied by Biogems

Cross Reactivity:
Mouse
Research Interest

Country Of Origin: USA

Not for human use.