Animal-Free Cytokines

Animal-Free Recombinant Human CNTF

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Product Details

Catalogue Number: AF-450-13
Description:
Animal-Free Recombinant Human CNTF

CNTF is a potent neural factor that was originally characterized as a vital factor for the survival of chick ciliary neurons in vitro. CNTF is also important for the survival of other neural cell types, including primary sensory neurons, motor neurons, basal forebrain neurons and type 2 astrocytes. CNTF is highly conserved across species and exhibits cross-species bioactivity. Recombinant Human CNTF is synthesized as a 199 amino acid polypeptide (22.8 kDa) lacking a hydrophobic N-terminal signal for secretion.

Manufactured using all Animal-Free reagents.

Source: E.coli

Synonyms: Ciliary Neurotrophic Factor

AA Sequence: AFTEHSPLTP HRRDLCSRSI WLARKIRSDL TALTQSYVKH QGLNKNINLD SADGMPVAST DQWSQLTQAQ RLQQNLQAYR TFHVLLARLL QDQQVHFTPT QGDFHQAIHT LLLQVAAFAY QIQQLMILLQ YKIPRNQADG MPINVGDGGL FQKKLWGLKV LQQLSQWTVR SIHDLRFISS HQTGIPARGS HYIANNKKM

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to stimulate proliferation of human TF-1 cells using an ED50 concentration range of 50-150 ng/ml.

Calculated Molecular Weight: 22.8 kDa

Accession Number: P26441

Gene ID: 1270

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Peng, Y
Title
Molecular Classification and Comparative Taxonomics of Foveal and Peripheral Cells in Primate Retina.
Citation
Cell; 176(5) pg1222-1237.e22
PubMed Id
First Author
Yun, Y
Title
CRISPR-mediated Gene Correction Links the ATP7A M1311V Mutations With Amyotrophic Lateral Sclerosis Pathogenesis in One Individual
Citation
Communications Biology; 3(1) pg33
PubMed Id