Recombinant Human FGF-4 1 ReviewsSubmit a Review Product Details Catalog Number: 100-31 Description: FGF-4 is a heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-4 signals through FGFR 1c, 2c, 3c, and 4. Recombinant Human FGF-4 is a 19.7 kDa protein consisting of 182 amino acid residues. Source: E.coli Synonyms: Fibroblast Growth Factor-4, HST-1, Transforming protein KS3, HBGF-4 AA Sequence: GRGGAAAPTA PNGTLEAELE RRWESLVALS LARLPVAAQP KEAAVQSGAG DYLLGIKRLR RLYCNVGIGF HLQALPDGRI GGAHADTRDS LLELSPVERG VVSIFGVASR FFVAMSSKGK LYGSPFFTDE CTFKEILLPN NYNAYESYKY PGMFIALSKN GKTKKGNRVS PTMKVTHFLP RL Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg. Calculated Molecular Weight: 19.7 kDa Accession Number: P08620 Gene ID: 2249 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Note: 1mg will be provided as 2x500μg. Cross Reactivity Cited in References: Chicken, Human, Mouse, Pig, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Organoids Angiogenesis/Cardiovascular Bone, Skeletal, Cartilage Cancer FGF Superfamily Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing Recent Citations First Author Capatina, N Title Elevated homocysteine activates unfolded protein responses and causes aberrant trophoblast differentiation and mouse blastocyst development. Citation Physiological Reports; 10(18) pge15467 PubMed ID 36117391 First Author Ryu, T Y Title Human gut-microbiome-derived propionate coordinates proteasomal degradation via HECTD2 upregulation to target EHMT2 in colorectal cancer. Citation The ISME Journal; 16(5) pg1205-1221 PubMed ID 34972816 First Author Muto, M Title Intersection of regulatory pathways controlling hemostasis and hemochorial placentation. Citation Proceedings of the National Academy of Sciences of the United States of America; 118(50) PubMed ID 34876522 Product Reviews Existing reviews Great Product We have been using this FGF-4 product to culture Trophoblast stem cells successfully. Always arrives quickly and works well. From: Alison | Date: 07/08/2020 × Great Product We have been using this FGF-4 product to culture Trophoblast stem cells successfully. Always arrives quickly and works well. From: Alison | Date: 07/08/2020 Close
