Growth Factors & Cytokines

Recombinant Human FGF-9

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Product Details

Catalogue Number: 100-23
Description:


Recombinant Human FGF-9

FGF-9 is a heparin-binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-9 targets glial cells, astrocytes cells and other cells that express FGFR 1c, 2c, 3b, 3c, and 4. Recombinant Human FGF-9 is a 23.2 kDa protein consisting of 206 amino acid residues.

Source: E.coli

Synonyms: Fibroblast Growth Factor-9, GAF (Glia-activating factor), HBGF-9

AA Sequence: PLGEVGNYFG VQDAVPFGNV PVLPVDSPVL LSDHLGQSEA GGLPRGPAVT DLDHLKGILR RRQLYCRTGF HLEIFPNGTI QGTRKDHSRF GILEFISIAV GLVSIRGVDS GLYLGMNEKG ELYGSEKLTQ ECVFREQFEE NWYNTYSSNL YKHVDTGRRY YVALNKDGTP REGTRTKRHQ KFTHFLPRPV DPDKVPELYK DILSQS

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg.

Calculated Molecular Weight: 23.2 kDa

Accession Number: P31371

Gene ID: 2254

Note:

1mg will be provided as 2x500μg.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Zhang, X
Title
Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family.
Citation
The Journal of Biological Chemistry; 281(23) pg15694-700
PubMed Id
First Author
Hu, H
Title
Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms.
Citation
Cancer Cell; 39(11) pg1531-1547.e10
PubMed Id
First Author
Savchenko, E
Title
FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes.
Citation
Scientific Reports; 9(1) pg9610
PubMed Id