Animal-Free Cytokines

Animal-Free Recombinant Human FGF-basic (154 a.a.)

Product Details

Catalogue Number: AF-100-18B
Description:
Animal-Free Recombinant Human FGF-basic (154 a.a.)

FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated, heparin-binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant Human FGF-basic is a 17.2 kDa protein consisting of 154 amino acid residues.

Qualified for stem cell use.

Manufactured using all Animal-Free reagents.

Source: E.coli

Synonyms: Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin

AA Sequence: AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.

This product has been tested against the WHO standard. International Unit information can be found here.

Animal-Free Recombinant Human FGF-basic (154 a.a.) Biological Activity Graph

Calculated Molecular Weight: 17.2 kDa

Accession Number: P09038

Gene ID: 2247

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Zhang, X
Title
FOXF2 oppositely regulates stemness in luminal and basal-like breast cancer cells through the Wnt/beta-catenin pathway.
Citation
The Journal of Biological Chemistry; 298(7) pg102082
PubMed Id
First Author
Liu, Y
Title
Paradoxical role of β8 integrin on angiogenesis and vasculogenic mimicry in glioblastoma.
Citation
Cell death & disease; 13(6) pg536
PubMed Id
First Author
Blackmore, D G
Title
An exercise "sweet spot" reverses cognitive deficits of aging by growth-hormone-induced neurogenesis.
Citation
Iscience; 24(11) pg103275
PubMed Id

product.subtitle.productreviews

Existing reviews
Worked well for research purposes
We used this product in one of our orthopedic research studies. Product arrived quickly and was packaged well. Would purchase again.
From:  Emilie | Date:  26/08/2020