Recombinant Human Galectin-1 1 ReviewsSubmit a Review Product Details Catalog Number: 450-39 Description: Lectins, of either plant or animal origin, are carbohydrate-binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T cells and T leukemia cell lines, and inhibits the protein phosphatase activity of CD45. Recombinant Human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues. Source: E.coli Synonyms: Galactose-specific lectin-1, Beta-galactoside-binding lectin L-14-I, Galaptin, 14 kDa lectin, S-LAC lectin-1 AA Sequence: ACGLVASNLN LKPGECLRVR GEVAPDAKSF VLNLGKDSNN LCLHFNPRFN AHGDANTIVC NSKDGGAWGT EQREAVFPFQ PGSVAEVCIT FDQANLTVKL PDGYEFKFPN RLNLEAINYM AADGDFKIKC VAFD Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 µg/ml with a peak response obtained at 250 µg/ml. Calculated Molecular Weight: 14.5 kDa Accession Number: P09382 Gene ID: 3956 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Cross Reactivity Cited in References: Human, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Apoptosis Cancer Immune System Neurobiology Stem Cells & Differentiation Recent Citations First Author Huang, Y Title Combination of tumor necrosis factor-α and epidermal growth factor induces the adrenergic-to-mesenchymal transdifferentiation in SH-SY5Y neuroblastoma cells. Citation Cancer Science; 112(2) pg715-724 PubMed ID 33277754 First Author Sweeney, J G Title Loss of GCNT2/I-branched glycans enhances melanoma growth and survival. Citation Nature Communications; 9(1) pg3368 PubMed ID 30135430 First Author Giovannone, N Title Galectin-9 suppresses B cell receptor signaling and is regulated by I-branching of N-glycans. Citation Nature Communications; 9(1) pg3287 PubMed ID 30120234 Product Reviews Existing reviews good ELISA results Used for ELISA binding assay, got good results. Did not do any assays for function. From: Lucia | Date: 03/08/2021 × good ELISA results Used for ELISA binding assay, got good results. Did not do any assays for function. From: Lucia | Date: 03/08/2021 Close
