Animal-Free Cytokines

Animal-Free Recombinant Human IL-7

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Product Details

Catalogue Number: AF-200-07
Description:

IL-7 is a hematopoietic growth factor that primarily affects early B and T cells.  Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors, such as ConA and IL-2.  Human and murine IL-7 are cross-species reactive.  Recombinant Human IL-7 is a 17.5 kDa protein containing 153 amino acid residues.

Manufactured using all Animal-Free reagents.

Source: E.coli

Synonyms: Interleukin-7, Lymphopoietin 1(LP-1), pre-B-cell factor

AA Sequence: MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to stimulate the proliferation of mouse 2E8 cells. The expected ED50 is ≤0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.

This product has been tested against the WHO standard. International Unit information can be found here.

Calculated Molecular Weight: 17.5 kDa

Accession Number: P13232

Gene ID: 3574

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Takata, H
Title
Functional heterogeneity of human effector CD8+ T cells.
Citation
Blood; 119(6) pg1390-8
PubMed Id
First Author
To, J
Title
A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function
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Communications Biology; 4(1) pg56
PubMed Id
First Author
Rabenhorst, A
Title
Mast cells play a protumorigenic role in primary cutaneous lymphoma.
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Blood; 120(10) pg2042-54
PubMed Id