IL-7 is a hematopoietic growth factor that primarily affects early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors, such as ConA and IL-2. Human and murine IL-7 are cross-species reactive. Recombinant Human IL-7 is a 17.5 kDa protein containing 153 amino acid residues.
Manufactured using all Animal-Free reagents.
Interleukin-7, Lymphopoietin 1(LP-1), pre-B-cell factor
MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH
≥ 98% by SDS-PAGE gel and HPLC analyses.
Determined by its ability to stimulate the proliferation of mouse 2E8 cells. The expected ED50 is ≤0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
This product has been tested against the WHO standard. International Unit information can be found here.
Calculated Molecular Weight:
Not for human use.