Animal-Free Recombinant Human IL-7 0 ReviewsSubmit a Review Product Details Catalogue Number: AF-200-07 Description: IL-7 is a hematopoietic growth factor that primarily affects early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors, such as ConA and IL-2. Human and murine IL-7 are cross-species reactive. Recombinant Human IL-7 is a 17.5 kDa protein containing 153 amino acid residues. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Interleukin-7, Lymphopoietin 1(LP-1), pre-B-cell factor AA Sequence: MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to stimulate the proliferation of mouse 2E8 cells. The expected ED50 is ≤0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg. This product has been tested against the WHO standard. International Unit information can be found here. Calculated Molecular Weight: 17.5 kDa Accession Number: P13232 Gene ID: 3574 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) crossreactivity: Human, Human + Hamster, Human + Virus, Mouse, Rabbit References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest CAR T Cell Cancer Immune System Inflammation Stem Cells & Differentiation product.subtitle.recentcitations First Author Kluesner, M G Title CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary and immortalized cells Citation Nature Communications; 12(1) pg2437 PubMed Id 33893286 First Author To, J Title A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function Citation Communications Biology; 4(1) pg56 PubMed Id 33420321 First Author Packiriswamy, N Title Oncolytic measles virus therapy enhances tumor antigen-specific T-cell responses in patients with multiple myeloma Citation Leukemia; PubMed Id 32327728
