Animal-Free Cytokines

Animal-Free Recombinant Human KGF (FGF-7)

Product Details

Catalogue Number: AF-100-19
Description:

KGF (FGF-7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. KGF (FGF-7) is a mitogen factor specific for epithelial cells and keratinocytes. KGF (FGF-7) signals through FGFR 2b. KGF (FGF-7) plays a role in kidney and lung development, as well as in angiogenesis and wound healing. Recombinant Human KGF (FGF-7) is an 18.9 kDa protein consisting of 163 amino acid residues.

Manufactured using all Animal-Free reagents.

Source: E.coli

Synonyms: Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7

AA Sequence: CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM AIT

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by a cell proliferation assay using 4MBr-5 cells. The expected ED50 for this effect is 0.1-15 ng/ml.

This product has been tested against the WHO standard. International Unit information can be found here.

Calculated Molecular Weight: 18.9 kDa

Accession Number: P21781

Gene ID: 2252

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Maitra, M
Title
Mutant surfactant A2 proteins associated with familial pulmonary fibrosis and lung cancer induce TGF-β1 secretion.
Citation
Proceedings of the National Academy of Sciences of the United States of America; 109(51) pg21064-9
PubMed Id
First Author
Rezanejad, H
Title
Heterogeneity of SOX9 and HNF1β in Pancreatic Ducts Is Dynamic.
Citation
Stem Cell Reports; 10(3) pg725-738
PubMed Id
First Author
Ulsamer, A
Title
Axin pathway activity regulates in vivo pY654-β-catenin accumulation and pulmonary fibrosis.
Citation
The Journal of Biological Chemistry; 287(7) pg5164-72
PubMed Id

product.subtitle.productreviews

Existing reviews
Good product
This product worked well for my project.  The price is reasonable and lower than most of vendors.
From:  Jin | Date:  26/08/2020