Chemokines

Recombinant Human MIP-3β (CCL19)

Product Details

Catalogue Number: 300-29B
Description:
Recombinant Human MIP-3β (CCL19)

MIP-3β is a CC chemokine, expressed in the thymus, lymph nodes, and in activated bone marrow stromal cells that signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes, and myeloid progenitor cells. Human MIP-3β is active on murine cells. Recombinant Human MIP-3β is an 8.8 kDa protein containing 77 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Source: E.coli

Synonyms: Macrophage Inflammatory Protein-3β, CCL19, ELC, Exodus-3, SCYA19

AA Sequence: GTNDAEDCCL SVTQKPIPGY IVRNFHYLLI KDGCRVPAVV FTTLRGRQLC APPDQPWVER IIQRLQRTSA KMKRRSS

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human T cells using a concentration of 10.0-50.0 ng/ml.

Calculated Molecular Weight: 8.8 kDa

Accession Number: Q99731

Gene ID: 6363

Note:

1mg will be provided as 2x500μg.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Du, Y
Title
Chemokines form nanoparticles with DNA and can superinduce TLR-driven immune inflammation.
Citation
The Journal of Experimental Medicine; 219(7)
PubMed Id
First Author
Gurusamy, M
Title
G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators.
Citation
Nature Communications; 12(1) pg6798
PubMed Id
First Author
Lee, A W
Title
A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.
Citation
The Journal of Biological Chemistry; 294(29) pg11199-11212
PubMed Id

product.subtitle.productreviews

Existing reviews
CCL19
This product works very well at a concentration of 10 ng/ml.
From:  Meshach | Date:  22/07/2020