Recombinant Human MIP-3β (CCL19) 1 ReviewsSubmit a Review Product Details Catalog Number: 300-29B Description: MIP-3β is a CC chemokine, expressed in the thymus, lymph nodes, and in activated bone marrow stromal cells that signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes, and myeloid progenitor cells. Human MIP-3β is active on murine cells. Recombinant Human MIP-3β is an 8.8 kDa protein containing 77 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. Source: E.coli Synonyms: Macrophage Inflammatory Protein-3β, CCL19, ELC, Exodus-3, SCYA19 AA Sequence: GTNDAEDCCL SVTQKPIPGY IVRNFHYLLI KDGCRVPAVV FTTLRGRQLC APPDQPWVER IIQRLQRTSA KMKRRSS Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human T cells using a concentration of 10.0-50.0 ng/ml. Calculated Molecular Weight: 8.8 kDa Accession Number: Q99731 Gene ID: 6363 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Note: 1mg will be provided as 2x500μg. Cross Reactivity Cited in References: Bacteria, Human, Human + Mouse, Monkey, Mouse, Zebra Fish References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Wound Healing Recent Citations First Author Du, Y Title Chemokines form nanoparticles with DNA and can superinduce TLR-driven immune inflammation. Citation The Journal of Experimental Medicine; 219(7) PubMed ID 35640018 First Author Gurusamy, M Title G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators. Citation Nature Communications; 12(1) pg6798 PubMed ID 34815397 First Author Lee, A W Title A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins. Citation The Journal of Biological Chemistry; 294(29) pg11199-11212 PubMed ID 31167786 Product Reviews Existing reviews CCL19 This product works very well at a concentration of 10 ng/ml. From: Meshach | Date: 22/07/2020 × CCL19 This product works very well at a concentration of 10 ng/ml. From: Meshach | Date: 22/07/2020 Close
