Chemokines

Recombinant Human MIP-3β (CCL19)

Product Details

Catalogue Number: 300-29B
Description:

MIP-3β is a CC chemokine, expressed in the thymus, lymph nodes, and in activated bone marrow stromal cells that signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes, and myeloid progenitor cells. Human MIP-3β is active on murine cells. Recombinant Human MIP-3β is an 8.8 kDa protein containing 77 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Source: E.coli

Synonyms: Macrophage Inflammatory Protein-3β, CCL19, ELC, Exodus-3, SCYA19

AA Sequence: GTNDAEDCCL SVTQKPIPGY IVRNFHYLLI KDGCRVPAVV FTTLRGRQLC APPDQPWVER IIQRLQRTSA KMKRRSS

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human T cells using a concentration of 10.0-50.0 ng/ml.

Calculated Molecular Weight: 8.8 kDa

Accession Number: Q99731

Gene ID: 6363

Note:

1mg will be provided as 2x500μg.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Shinde, P
Title
Compromised functionality of monocyte-derived dendritic cells in multiple myeloma patients may limit their use in cancer immunotherapy.
Citation
Scientific Reports; 8(1) pg5705
PubMed Id
First Author
Watts, A O
Title
β-Arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKR.
Citation
The Journal of Biological Chemistry; 288(10) pg7169-81
PubMed Id
First Author
Brown, M
Title
Lymphatic exosomes promote dendritic cell migration along guidance cues.
Citation
The Journal of Cell Biology; 217(6) pg2205-2221
PubMed Id

product.subtitle.productreviews

Existing reviews
CCL19
This product works very well at a concentration of 10 ng/ml.
From:  Meshach | Date:  22/07/2020