PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes, and has been shown to inhibit angiogenesis. Recombinant Human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines.
Platelet Factor-4, CXCL4, Oncostatin A, Ironplact
EAEEDGDLQC LCVKTTSQVR PRHITSLEVI KAGPHCPTAQ LIATLKNGRK ICLDLQAPLY KKIIKKLLES
≥ 98% by SDS-PAGE gel and HPLC analyses.
Determined by its ability to chemoattract human fibroblasts using a concentration range of 1.0-10.0 ng/ml.
Calculated Molecular Weight:
Not for human use.