Recombinant Human PlGF-1 0 ReviewsSubmit a Review Product Details Catalogue Number: 100-06 Description: PlGF-1 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-1 is expressed in placental tissues, the colon, and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor, and stimulates endothelial cell proliferation and migration. Recombinant Human PlGF-1 is a 29.7 kDa disulfide-linked homodimeric protein of two 132 amino acid polypeptide chains. Source: E.coli Synonyms: Placenta Growth Factor-1, PlGF, PGF AA Sequence (monomer): MLPAVPPQQW ALSAGNGSSE VEVVPFQEVW GRSYCRALER LVDVVSEYPS EVEHMFSPSC VSLLRCTGCC GDENLHCVPV ETANVTMQLL KIRSGDRPSY VELTFSQHVR CECRPLREKM KPERCGDAVP RR Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human monocytes of using a concentration range of 1.0-10.0 ng/ml. Calculated Molecular Weight: 29.7 kDa Accession Number: P49763 Gene ID: 5228 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Mouse, References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Cancer Immune System Inflammation Neurobiology Stem Cells & Differentiation product.subtitle.recentcitations First Author Lechertier, T Title Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth. Citation Nature Communications; 11(1) pg2810 PubMed Id 32499572 First Author Kojovic, D Title Role of Elevated SFLT-1 on the Regulation of Placental Transporters in Women With Pre-Eclampsia. Citation Clinical And Translational Science; 13(3) pg580-588 PubMed Id 31917511 First Author Ishihara, J Title Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing. Citation Nature Communications; 9(1) pg2163 PubMed Id 29867149
