Animal-Free Recombinant Murine EGF 0 ReviewsSubmit a Review Product Details Catalog Number: AF-315-09 Description: EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor). Recombinant Murine EGF is a 6.0 kDa globular protein containing 53 amino acid residues, including 3 intramolecular disulfide bonds. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Epidermal Growth Factor, Urogastrone, URG AA Sequence: NSYPGCPSSY DGYCLNGGVC MHIESLDSYT CNCVIGYSGD RCQTRDLRWW ELR Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 was determined by a cell proliferation assay using BALB/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. Calculated Molecular Weight: 6 kDa Accession Number: P01132 Gene ID: 13645 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) Cross Reactivity Cited in References: Human, Mouse References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Organoids Angiogenesis/Cardiovascular Cancer Cell Culture Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing Diabetes/Weight Regulation Recent Citations First Author Blackmore, D G Title An exercise "sweet spot" reverses cognitive deficits of aging by growth-hormone-induced neurogenesis. Citation Iscience; 24(11) pg103275 PubMed ID 34761193 First Author Lu, J Title Characterization of an in vitro 3D intestinal organoid model by using massive RNAseq-based transcriptome profiling Citation Scientific Reports; 11(1) pg16668 PubMed ID 34404908 First Author Mu, W Title Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice Citation Nature Communications; 12(1) pg2288 PubMed ID 33863883
