Growth Factors & Cytokines

Recombinant Murine FGF-21

Product Details

Catalog Number: 450-56
Description:

FGF-21 is a secreted growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-21, in the presence of β-Klotho as a protein cofactor, signals through the FGFR 1c and 4 receptors, and stimulates insulin-independent glucose uptake by adipocytes. Recombinant Murine FGF-21 is a 20.1 kDa protein containing 182 amino acid residues.

Source: E.coli

Synonyms: Fibroblast Growth Factor-21, FGFL

AA Sequence: MAYPIPDSSP LLQFGGQVRQ RYLYTDDDQD TEAHLEIRED GTVVGAAHRS PESLLELKAL KPGVIQILGV KASRFLCQQP DGALYGSPHF DPEACSFREL LLEDGYNVYQ SEAHGLPLRL PQKDSPNQDA TSWGPVRFLP MPGLLHEPQD QAGFLPPEPP DVGSSDPLSM VEPLQGRSPS YAS

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to stimulate the proliferation of murine NIH-3T3 cells.

Calculated Molecular Weight: 20.1 kDa

Accession Number: Q9JJN1

Gene ID: 56636

Research Interest

Country Of Origin: USA

Not for human use.